The Role of Epigenetics, Gut Microbiota and Nutrition in Human Wellbeing
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrigenetics and Nutrigenomics".
Deadline for manuscript submissions: 25 June 2026 | Viewed by 57
Special Issue Editors
Interests: microbiota; microbiome; epigenetics; epigenetic biomarkers; DNA methylation modifications; mitochondrial DNA methylation; aging; nutrition; multi-drug resistance
Special Issues, Collections and Topics in MDPI journals
Interests: microbiota; microbiome; epigenetics; epigenetic biomarkers; DNA methylation modifications; mitochondrial DNA methylation; aging; nutrition; multi-drug resistance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Increasing evidence indicates that specific nutrients and dietary patterns, especially during critical periods like early development, can influence long-term health outcomes by modulating the epigenetic markers at both the nucleic acid and chromatin levels. This may, at least in part, be explained by a dynamic interconnection among nutrition, epigenetics, and the gut microbiota. Indeed, dietary components significantly influence the composition and function of the gut microbiota, which then produces metabolites that act as substrates or regulators for epigenetic enzymes that can alter the host's epigenome and, ultimately, influence host health. Reciprocally, the host's epigenome can influence microbial composition. It follows that an extensive comprehension of this triad is crucial for maintaining health and preventing or attenuating the course of disease.
In this Special Issue, we would like to present contributions addressing insights on the interplay between diet, gut microbiota, and host epigenetics in modulating human wellbeing.
Dr. Dina Bellizzi
Dr. Patrizia D'Aquila
Guest Editors
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Keywords
- epigenetics
- DNA methylation
- histone modifications
- nutrition
- nutrients
- diet
- methyl donor supplementation
- one-carbon metabolism
- bioactive compounds
- gut microbiota
- microbiota–host interactions
- microbiota-derived metabolites
- personalized nutrition
- aging
- well-being
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