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Nutrients
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Advances in Dietary Biomarkers for Assessing Food Intake and Their...
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Advances in Dietary Biomarkers for Assessing Food Intake and Their Impact on Health Outcomes

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: closed (25 September 2024) | Viewed by 1898

Special Issue Editor

Prof. Dr. Geng Zong

E-Mail Website
Guest Editor
CAS Key Laboratory of Nutrition and Metabolism, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China
Interests: food biomarkers; nutrition epidemiology; dietary fat; diabetes; obesity

Special Issue Information

Dear Colleagues,

Diet is a pivotal, modifiable risk factor for non-communicable diseases, including cardiometabolic disorders, cancers, and neurodegenerative conditions. In epidemiological research, questionnaire-based dietary assessments are subject to large measurement errors and biases that can compromise the validity of findings. Existing studies have shown that food-derived molecules in biological samples may be an objective supplement to assess specific food components, thus enhancing the precision of dietary assessments.

We invite the submission of original research studies and comprehensive literature reviews for a Special Issue focused on the discovery, validation, and application of dietary biomarkers. Contributions should aim to improve the accuracy of dietary assessments and potential understanding on diet-disease relationship. We are particularly interested in studies that

  • Identify and validate new biomarkers of foods and other dietary exposures;
  • Compare the efficacy of biomarker-based dietary assessments with traditional questionnaire-based methods;
  • Examine the interplay between diet, genetic predispositions, and the gut microbiota on these biomarkers;
  • Apply food and nutrient biomarkers to observational and interventional studies.

This Special Issue seeks to advance the field of nutritional epidemiology by integrating innovative biomarker research with traditional dietary assessment techniques.

Prof. Dr. Geng Zong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomarkers
  • diet assessment
  • nutritional epidemiology
  • nutrition interventions
  • non-communicable diseases

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

15 pages, 1870 KiB  
Article
The Relationships among the Urinary Iodine Concentration, Selenium Intake, and Thyroid Antibodies in Adults, Including the Interaction between Iodine and Selenium: National Health and Nutrition Examination Survey 2007–2012
by Chenyu Zhang, Haoyu Wang, Weiping Teng and Zhongyan Shan
Nutrients 2024, 16(20), 3443; https://doi.org/10.3390/nu16203443 - 11 Oct 2024
Cited by 2 | Viewed by 1491
Abstract
Objectives: The objective of this study was to examine the urinary iodine concentration (UIC)–thyroid autoimmunity (TAI) association and UIC–selenium intake interaction in U.S. adults. Methods: We analyzed 2007–2012 National Health and Nutrition Examination Survey (NHANES) data on ≥20-year-old adults (n = 6612). [...] Read more.
Objectives: The objective of this study was to examine the urinary iodine concentration (UIC)–thyroid autoimmunity (TAI) association and UIC–selenium intake interaction in U.S. adults. Methods: We analyzed 2007–2012 National Health and Nutrition Examination Survey (NHANES) data on ≥20-year-old adults (n = 6612). Their food and supplemental selenium intake was measured. The associations of the UIC and selenium intake with thyroid peroxidase antibody (TPOAb) positivity, thyroglobulin antibody (TgAb) positivity, and TAI were assessed via weighted multivariable logistic regression. Interaction and subgroup analyses were conducted. Nonlinear relationships were explored and visualized via restricted cubic splines (RCSs). Results: Compared with a UIC 100~200 μg/L, a UIC 500~800 μg/L was associated with a 57% increased TPOAb positivity risk (OR = 1.57 [CI = 1.07–2.30]; p = 0.022), a one-fold greater TgAb positivity risk (OR = 2.00 [CI = 1.10–3.65]; p = 0.025), and a 62% increased TAI risk (OR = 1.62 [CI = 1.07–2.45]; p = 0.024). Nonlinear relationships between the UIC and thyroid antibody positivity were observed. According to the univariate models, each 1 μg increase in selenium intake was associated with a 0.049 IU/mL decrease in the TPOAb levels (β [95% CI] = −0.049 [−0.092–−0.005]; p = 0.028). In the low-selenium group, a UIC of 200~300 μg/L was a risk factor for TPOAb positivity (p = 0.046). At a moderate level of selenium intake, a UIC of 300~800 μg/L significantly increased the TPOAb positivity risk (all p < 0.05). At a high level of selenium intake, the UIC and TPOAb positivity risks were not significantly associated (all p > 0.05). Conclusions: A UIC of 500~800 μg/L is an independent TAI risk factor. The selenium intake modifies the UIC–thyroid antibody positivity relationship, with the association disappearing at high selenium levels. Full article
(This article belongs to the Special Issue Advances in Dietary Biomarkers for Assessing Food Intake and Their Impact on Health Outcomes)
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