CRISPR/Cas Technology Applied to the Study of Non-coding RNAs in Human Disease
This special issue belongs to the section "Clinical Applications of Non-Coding RNA".
Special Issue Information
Dear Colleague,
Originally used by bacteria to protect themselves against viruses, CRISPR/Cas system-based editing of DNA and RNA has, in recent years, been adapted to a wide variety of purposes, including the study of complex biological processes, the design of new therapeutic approaches, and the development of new biotechnological tools.
This Special Issue will collect original research articles and communications in which CRISPR/Cas technology is used in human disease:
- To study the biological role played by non-coding RNAs, through the modulation of their expression at the genomic, transcriptional, or post-transcriptional level; through the identification of RNA and protein species directly bound to them; or through their visualization and tracking inside human cells.
- To target non-coding RNAs for therapeutic purposes.
Submissions describing in vivo data obtained in animal models are strongly encouraged.
This Special Issue will also include concept articles in which, rather than giving an overview of the literature, authors provide insights and explain ideas that can contribute to stimulate discussion and move the field forward.
Prof. Dr. Pier Paolo Pandolfi
Dr. Laura Poliseno
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Non-Coding RNA is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- CRISPR/Cas system
- Cas9
- Cas13
- genome editing
- CRISPRa/i
- RNA knock-down
- RNA editing
- RNA immunoprecipitation/pull-down
- RNA tracking
- CRISPR-based therapeutics
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Published Papers
Non-Coding RNA - ISSN 2311-553X