Special Issue "CRISPR/Cas Technology Applied to the Study of Non-coding RNAs in Human Disease"
A special issue of Non-Coding RNA (ISSN 2311-553X).
Deadline for manuscript submissions: 31 August 2022 | Viewed by 5598
Interests: cancer genetics; tumor suppressor genes and oncogenes; non-coding RNAs; microRNAs; circ-RNAs; ceRNAs; pseudogenes
Interests: melanoma; BRAFV600E isoforms; microRNAs; ceRNAs; pigmentation; melanoma modeling in zebrafish and mouse; attenuated Listeria monocytogenes; pseudogenes
Special Issues, Collections and Topics in MDPI journals
Special Issue in Non-Coding RNA: Women’s Special Issue Series: Noncoding RNAs and Diseases
Special Issue in International Journal of Molecular Sciences: RNA Metabolism: Role in Human Pathophysiology and Its Potential for Therapeutic Interventions
Originally used by bacteria to protect themselves against viruses, CRISPR/Cas system-based editing of DNA and RNA has, in recent years, been adapted to a wide variety of purposes, including the study of complex biological processes, the design of new therapeutic approaches, and the development of new biotechnological tools.
This Special Issue will collect original research articles and communications in which CRISPR/Cas technology is used in human disease:
- To study the biological role played by non-coding RNAs, through the modulation of their expression at the genomic, transcriptional, or post-transcriptional level; through the identification of RNA and protein species directly bound to them; or through their visualization and tracking inside human cells.
- To target non-coding RNAs for therapeutic purposes.
Submissions describing in vivo data obtained in animal models are strongly encouraged.
This Special Issue will also include concept articles in which, rather than giving an overview of the literature, authors provide insights and explain ideas that can contribute to stimulate discussion and move the field forward.
Prof. Dr. Pier Paolo Pandolfi
Dr. Laura Poliseno
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Non-Coding RNA is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- CRISPR/Cas system
- genome editing
- RNA knock-down
- RNA editing
- RNA immunoprecipitation/pull-down
- RNA tracking
- CRISPR-based therapeutics
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: ncRNAs associated with transmissible cancers in Tasmanian devil, domestic dog and bivalves
Authors: Nicholas C. Lister1, Ashley M. Milton1, Benjamin Hanrahan1 and Paul D. Waters1
Affiliation: Biotechnology and Biomedical Sciences, The University of New South Wales, Sydney, Australia
Title: To be determined
Authors: Laura Poliseno
Affiliation: Oncogenomics Unit, Institute of Clinical Physiology (IFC), National Research Council (CNR); and Core Research Laboratory (CRL), Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Via Moruzzi 1, 56124 Pisa, Italy
Title: To be determined
Authors: Kevin V. Morris
Affiliation: Department of Molecular and Experimental Medicine; The Scripps Research Institute; La Jolla, CA USA
Title: High-throughput technologies and approaches to study the non-coding genome
Authors: Bester Assaf
Affiliation: Technion Israel Institute of Technology / Life Sciences