Nanocomposites for Bio-MEMS/NEMS Applications

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Nanoelectronics, Nanosensors and Devices".

Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 5168

Special Issue Editor


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Guest Editor
Department of Biomedical Engineering, Centre for Innovation in Medical Engineering, Faculty of Engineering, University Malaya, Kuala Lumpur, Malaysia
Interests: nanocomposites; nanomaterials; micro/nano device; MEMS; NEMS; bionanotechnology

Special Issue Information

Dear Colleagues,

This Special Issue intends to advocate the revolution on the advancements and applications of various nanocomposites in the development of robust and reliable bio-MEMS/NEMS devices. Nanocomposites have recently achieved impetus in the context of micro/nano-electro-mechanical systems (MEMS/NEMS) development due to their exceptional physiochemical properties. The nanocomposites are composed of a branch of zero to multidimensional structured nanosized particles within a matrix, known for their greater electrical, mechanical, and tribological properties at the nano scale. Particularly, the advancements in technology enable the incorporation of excellent properties of nanocomposites at the interface of bio-MEMS/NEMS devices. This novel approach is the best solution for common nanotribology and nanomechanics problems in bio-MEMS/NEMS system development which drastically compromises the device performance and reliability. Moreover, the large surface area of nanocomposites also helps to significantly enhance the bio-adhesion, biocompatibility and facilitate reaction kinetics through reduction of frictions on the bio-MEMS/NEMS surfaces.

This Special Issue will cover the recent advances in the use of nanocomposites for the fabrication of state-of-the-art bio-MEMS/NEMS devices for various applications areas encompassing the material properties/functionalities, basic design strategies, working mechanisms and relevant applications in real-world scenarios. Furthermore, the challenges associated incorporation of nanocomposites into bio-MEMS/NEMS devices and the future direction of this blooming research field will be also discussed.

Prof. Dr. Fatimah Binti Ibrahim
Guest Editor

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Published Papers (2 papers)

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Review

31 pages, 3776 KiB  
Review
Micro and Nano Interdigitated Electrode Array (IDEA)-Based MEMS/NEMS as Electrochemical Transducers: A Review
by Elyana Kosri, Fatimah Ibrahim, Aung Thiha and Marc Madou
Nanomaterials 2022, 12(23), 4171; https://doi.org/10.3390/nano12234171 - 24 Nov 2022
Cited by 12 | Viewed by 3381
Abstract
Micro and nano interdigitated electrode array (µ/n-IDEA) configurations are prominent working electrodes in the fabrication of electrochemical sensors/biosensors, as their design benefits sensor achievement. This paper reviews µ/n-IDEA as working electrodes in four-electrode electrochemical sensors in terms of two-dimensional (2D) planar IDEA and [...] Read more.
Micro and nano interdigitated electrode array (µ/n-IDEA) configurations are prominent working electrodes in the fabrication of electrochemical sensors/biosensors, as their design benefits sensor achievement. This paper reviews µ/n-IDEA as working electrodes in four-electrode electrochemical sensors in terms of two-dimensional (2D) planar IDEA and three-dimensional (3D) IDEA configurations using carbon or metal as the starting materials. In this regard, the enhancement of IDEAs-based biosensors focuses on controlling the width and gap measurements between the adjacent fingers and increases the IDEA’s height. Several distinctive methods used to expand the surface area of 3D IDEAs, such as a unique 3D IDEA design, integration of mesh, microchannel, vertically aligned carbon nanotubes (VACNT), and nanoparticles, are demonstrated and discussed. More notably, the conventional four-electrode system, consisting of reference and counter electrodes will be compared to the highly novel two-electrode system that adopts IDEA’s shape. Compared to the 2D planar IDEA, the expansion of the surface area in 3D IDEAs demonstrated significant changes in the performance of electrochemical sensors. Furthermore, the challenges faced by current IDEAs-based electrochemical biosensors and their potential solutions for future directions are presented herein. Full article
(This article belongs to the Special Issue Nanocomposites for Bio-MEMS/NEMS Applications)
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40 pages, 2560 KiB  
Review
Role of Nanomaterials in the Fabrication of bioNEMS/MEMS for Biomedical Applications and towards Pioneering Food Waste Utilisation
by Nuraina Anisa Dahlan, Aung Thiha, Fatimah Ibrahim, Lazar Milić, Shalini Muniandy, Nurul Fauzani Jamaluddin, Bojan Petrović, Sanja Kojić and Goran M. Stojanović
Nanomaterials 2022, 12(22), 4025; https://doi.org/10.3390/nano12224025 - 16 Nov 2022
Cited by 13 | Viewed by 3877
Abstract
bioNEMS/MEMS has emerged as an innovative technology for the miniaturisation of biomedical devices with high precision and rapid processing since its first R&D breakthrough in the 1980s. To date, several organic including food waste derived nanomaterials and inorganic nanomaterials (e.g., carbon nanotubes, graphene, [...] Read more.
bioNEMS/MEMS has emerged as an innovative technology for the miniaturisation of biomedical devices with high precision and rapid processing since its first R&D breakthrough in the 1980s. To date, several organic including food waste derived nanomaterials and inorganic nanomaterials (e.g., carbon nanotubes, graphene, silica, gold, and magnetic nanoparticles) have steered the development of high-throughput and sensitive bioNEMS/MEMS-based biosensors, actuator systems, drug delivery systems and implantable/wearable sensors with desirable biomedical properties. Turning food waste into valuable nanomaterials is potential groundbreaking research in this growing field of bioMEMS/NEMS. This review aspires to communicate recent progress in organic and inorganic nanomaterials based bioNEMS/MEMS for biomedical applications, comprehensively discussing nanomaterials criteria and their prospects as ideal tools for biomedical devices. We discuss clinical applications for diagnostic, monitoring, and therapeutic applications as well as the technological potential for cell manipulation (i.e., sorting, separation, and patterning technology). In addition, current in vitro and in vivo assessments of promising nanomaterials-based biomedical devices will be discussed in this review. Finally, this review also looked at the most recent state-of-the-art knowledge on Internet of Things (IoT) applications such as nanosensors, nanoantennas, nanoprocessors, and nanobattery. Full article
(This article belongs to the Special Issue Nanocomposites for Bio-MEMS/NEMS Applications)
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