Novel Strategies for Nanomaterials for Targeted Drug Delivery
A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".
Deadline for manuscript submissions: closed (15 August 2021) | Viewed by 9685
Special Issue Editors
Interests: nanotoxicology; in vitro; skin irritation; skin sensitization; cytotoxicity
Special Issues, Collections and Topics in MDPI journals
Interests: study of antioxidants of natural origin; development of models of ocular and dermal irritation in vitro; development of skin sensitization models in vitro; nanotoxicology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
There is a rapid progress in the development of nanotechnologies and nanomaterials, especially their use as nanocarriers for drug delivery. The number of papers related to nanomaterials and drug delivery has increased from no more than 20 in 2000 to more than 6 thousand in the last year. Their small size allows the penetration of drugs into cells in an easier manner. However, these nanomaterials can also facilitate penetration trough more complex systems such as the skin, eyes or the blood–brain barrier or increase the oral bioavailability of drugs with poor solubility, poor permeability, and/or poor stability in the gastrointestinal environment.
Nanocarriers may be tailored to control drug release and/or increase selective cell targeting, cellular uptake, drug solubility, and circulation time in order to maximize the therapeutic effects of drugs and minimize their side effects.
The kind of nanomaterials used with the objective of allowing drug delivery include nanoparticles in a wide variety as nanospheres, micelles, solid lipid nanoparticles, nanoliposomes, dendrimers, magnetic nanoparticles, and nanocapsules.
Nanomaterials for the delivery of anticancer drugs are one of the most studied but there are also other applications, such as the treatment of neurodegenerative and cardiovascular diseases, inflammatory disorders among others.
This Special Issue will cover research in this area with different types of nanomaterials and for different therapeutic purposes.
Prof. Dr. Maria Pilar Vinardell
Prof. Dr. Montse Mitjans Arnal
Guest Editors
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Keywords
- nanocarriers
- drug delivery
- therapy
- nanovesicles
- safety
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