Nanopesticides: Potential Benefits and Challenges in Agricultural Production

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 2262

Special Issue Editors


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Guest Editor
Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China
Interests: nanopesticides; nanobiotechnology; biosensors; nanocarrier-based gene delivery

E-Mail Website
Guest Editor
Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China
Interests: nanopesticides; disease and pest control; nanotechnology in agriculture

Special Issue Information

Dear Colleagues,

Nanopesticides are becoming an increasingly attractive formulation to enhance the effectiveness and durability of pesticides while reducing the quantity of active ingredients required. It is possible to optimize pesticide usage and mitigate issues, such as environmental contamination, bioaccumulation, and harmful organism resistance, with precision farming. The interactions between biological systems and nanopesticides are complex, and the potential risks posed by their toxicity to non-target organisms, transport, bioaccumulation, and interactions with other environmental pollutants must be carefully assessed.

In this Special Issue, we aim to discuss the current benefits and challenges associated with nanopesticides and enhance the assessment of their advantages and environmental risks. We hope to explore various aspects of nanopesticides, including their formulation types, preparation methods, characterization and application techniques, harmful organism control strategies, toxicology in plant and animal models, environmental risks, and current approaches in risk assessment and regulatory strategies.

We invite scientists from diverse backgrounds to submit original manuscripts, including articles, reviews, and short communications, on the benefits and challenges of using nanopesticides in agricultural production.

Prof. Dr. Zhanghua Zeng
Dr. Bo Cui
Guest Editors

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Keywords

  • nanopesticides
  • mechanism of action
  • nanopesticides’ advantages
  • formulation methods
  • controlled release
  • toxicology
  • environmental risks
  • pesticide fate
  • regulatory strategies

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Published Papers (2 papers)

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Research

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19 pages, 5510 KiB  
Article
pH and Pectinase Dual-Responsive Zinc Oxide Core-Shell Nanopesticide: Efficient Control of Sclerotinia Disease and Reduction of Environmental Risks
by Qiongmei Mai, Yu Lu, Qianyu Cai, Jianglong Hu, Yunyou Lv, Yonglan Yang, Liqiang Wang, Yuezhao Zhou and Jie Liu
Nanomaterials 2024, 14(24), 2022; https://doi.org/10.3390/nano14242022 - 16 Dec 2024
Viewed by 816
Abstract
Sclerotinia sclerotiorum is one of the fungi that cause plant diseases. It damages plants by secreting large amounts of oxalic acid and cell wall-degrading enzymes. To meet this challenge, we designed a new pH/enzyme dual-responsive nanopesticide Pro@ZnO@Pectin (PZP). This nanopesticide uses zinc oxide [...] Read more.
Sclerotinia sclerotiorum is one of the fungi that cause plant diseases. It damages plants by secreting large amounts of oxalic acid and cell wall-degrading enzymes. To meet this challenge, we designed a new pH/enzyme dual-responsive nanopesticide Pro@ZnO@Pectin (PZP). This nanopesticide uses zinc oxide (ZnO) as a carrier of prochloraz (Pro) and is encapsulated with pectin. When encountering oxalic acid released by Sclerotinia sclerotiorum, the acidic environment promotes the decomposition of ZnO; at the same time, the pectinase produced by Sclerotinia sclerotiorum can also decompose the outer pectin layer of PZP, thereby promoting the effective release of the active ingredient. Experimental data showed that PZP was able to achieve an efficient release rate of 57.25% and 68.46% when pectinase was added or under acidic conditions, respectively. In addition, in vitro tests showed that the antifungal effect of PZP was comparable to that of the commercial Pro (Pro SC) on the market, and its efficacy was 1.40 times and 1.32 times that of the Pro original drug (Pro TC), respectively. Crucially, the application of PZP significantly alleviated the detrimental impacts of Pro on wheat development. Soil wetting experiments have proved that PZP primarily remained in the soil, thereby decreasing its likelihood of contaminating water sources and reducing potential risks to non-target organisms. Moreover, PZP improved the foliar wettability of Pro, lowering the contact angle to 75.06°. Residue analyses indicated that PZP did not elevate prochloraz residue levels in tomato fruits compared to conventional applications, indicating that the nanopesticide formulation does not lead to excessive pesticide buildup. In summary, the nanopesticide PZP shows great promise for effectively managing Sclerotinia sclerotiorum while minimizing environmental impact. Full article
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Review

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26 pages, 2570 KiB  
Review
The Synthesis of Selenium Nanoparticles and Their Applications in Enhancing Plant Stress Resistance: A Review
by Xin Qin, Zijun Wang, Jie Lai, You Liang and Kun Qian
Nanomaterials 2025, 15(4), 301; https://doi.org/10.3390/nano15040301 - 16 Feb 2025
Cited by 2 | Viewed by 1064
Abstract
Nanoparticle-based strategies have emerged as transformative tools for addressing critical challenges in sustainable agriculture, offering precise modulation of plant–environment interactions through enhanced biocompatibility and stimuli-responsive delivery mechanisms. Among these innovations, selenium nanoparticles (SeNPs) present unique advantages due to their dual functionality as both [...] Read more.
Nanoparticle-based strategies have emerged as transformative tools for addressing critical challenges in sustainable agriculture, offering precise modulation of plant–environment interactions through enhanced biocompatibility and stimuli-responsive delivery mechanisms. Among these innovations, selenium nanoparticles (SeNPs) present unique advantages due to their dual functionality as both essential micronutrient carriers and redox homeostasis modulators. Compared to conventional selenium treatments, SeNPs offer a more efficient and environmentally friendly solution for improving plant resilience while minimizing toxicity, even at low doses. This review provides a comprehensive analysis of methods for synthesizing SeNPs, including chemical reduction, green synthesis using plant extracts, and biological techniques with microbial agents. Additionally, the review discusses the effects of SeNPs on biotic and abiotic stress responses in plants, focusing on how these nanoparticles activate stress-response pathways and enhance plant immune function. The primary objective of this study is to offer theoretical insights into the application of SeNPs for addressing critical challenges in modern agriculture, such as improving crop yield and quality under stress conditions. Moreover, the research highlights the role of SeNPs in advancing sustainable agricultural practices by reducing reliance on chemical fertilizers and pesticides. The findings underscore the transformative potential of SeNPs in crop management, contributing to a more sustainable and eco-friendly agricultural future. Full article
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