Mass Spectrometry Imaging 2021

Dear Colleagues,

One of the most exciting developments in the last few decades is the use of mass spectrometry as an imaging method, in which a histological section and matrix of 10-20 microns are dried on a sample holder. Thousands of mass spectra are then taken from the sample in a predetermined manner and with laser intensity; these are then displayed as images, using the appropriate software, based on the distribution of intensities for each m/z value. Imaging is an unlabeled technique that allows us to examine the localization of up to hundreds of molecules within a tissue in a single measurement and display them in 2D or even 3D. It also makes proteins, lipids and metabolites visible. The main advantages of mass spectrometry imaging for studying molecules’ location and distribution within tissue are that this analytical technique requires a small sample, and it can provide greater selectivity, more information and improved accuracy compared to others.

All researchers working in the field are cordially invited to contribute original research papers, short communications or reviews to this Special Issue of Molecules.

Dr. Laszlo Mark
Guest Editor

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