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Special Issue "Inhibitors of Plant Hormone Biosynthesis and Signaling"

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 1 November 2020

Special Issue Editor

Guest Editor
Dr. Wilfried Rozhon

Technical University of Munich, TUM School of Life Sciences Weihenstephan, Biotechnology of Horticultural Crops, Freising, Germany
Website | E-Mail
Interests: HPLC; UHPLC; GC; mass spectrometry; UV/VIS and IR spectroscopy; fluorimetry; separation of chiral molecules; plant metabolites and hormones; enzyme assays; inhibitors; plasmid biology; electrophoresis; quantitative PCR

Special Issue Information

Dear Colleagues,

Inhibitors of plant hormone biosynthesis and signaling are widely applied in agriculture and horticulture for the regulation of plant growth and development. Moreover, they are valuable tools for research. Inhibitors can be used to study developmental, physiological, and biochemical processes in different genetic backgrounds and plant species. Importantly, they are often useful to overcome functional redundancy, for instance, in polyploid species, where mutant approaches are difficult to realize. In addition, their application can be limited to a certain developmental stage, allowing transient modulation of desired processes.
The main topics of this Special Issue are the identification, synthesis, and characterization of novel inhibitors as well as improved synthesis of known compounds with special emphasis to green chemistry. Further, structure–activity relation studies for developing more active or stable compounds as well as identifying residues critical for activity are of great interest.
While for many compounds, a high activity for a certain process has been shown, information about the molecular targets and specificity are scarce. Similarly, although many inhibitors are chiral molecules, they are applied as mixtures of enantiomers, and it often remains unknown which stereoisomer shows biological activity. Thus, the identification of targets, specificity of novel and widely used compounds, and their stereochemical–activity relationship are also of main interest. That includes methods for enantiomer separation and enantioselective synthesis.
In order to exert its activity, the uptake of the compound and its transport within the plant are critical. Some compounds are also applied as prodrugs that require activation in the plant cell or tissue. In addition, many compounds interfering with plant hormone biosynthesis and signaling are modified and thus inactivated by plants.
Likewise, manuscripts about novel analytical methods for the detection of plant growth regulators in food, forage, and environmental samples are highly attractive topics for this Special Issue.
Original research articles, short communications, and reviews addressing the aforementioned or similar topics are welcome. For reviews, a brief proposal should be communicated prior to manuscript preparation to avoid overlap with other submissions.

Dr. Wilfried Rozhon
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • enzyme inhibitor
  • ligand–protein interactions
  • structure–activity relationship
  • stereochemistry
  • auxins
  • cytokinins
  • gibberellins
  • brassinosteroids
  • ethylene
  • salicylic acid
  • jasmonic acid
  • abscisic acid
  • strigolactones

Published Papers

This special issue is now open for submission.
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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