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Special Issue "Green Chemistry in Europe"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Green Chemistry".

Deadline for manuscript submissions: 31 March 2022.

Special Issue Editor

Dr. Rafał M. Łukasik
E-Mail Website
Guest Editor
Unidade de Bioenergia e Biorrefinerias, Laboratório Nacional de Energia e Geologia, I.P., Estrada do Paço do Lumiar 22, 1649-038 Lisboa, Portugal
Interests: green chemistry; biorefinery; bioenergy; biomass valorization; CO2; ionic liquids; value-added products; building blocks
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Climate change and environmental degradation are eminent risks for Europe and the world. To address these challenges, Europe established a new growth strategy embedded in a Green Deal action plan with the main aim in the transformation of the Union into a modern, resource-efficient and competitive economy, where there are no net emissions of greenhouse gases by 2050, economic growth is decoupled from resource use and no person and no place is left behind (A European Green Deal The main challenge of the European Green Deal is to make the EU's economy sustainable. It can be achieved by boosting the efficient use of resources by shifting to a greener and circular economy. To achieve these ambitious targets of the European Green Deal, all sectors have to invest into environmentally friendly technologies supporting industry to innovate and assisting the energy sector in its transition towards decarbonisation. Also, the UN Sustainable Development Goals (SDGs) depict a clean and comprehensive action plan with Green Chemistry as a tool to accomplished most of the goals. 

Hence, two the most relevant social and political actions in Europe and in the world put Green Chemistry at the centre of the action for a better and more sustainable future.

Considering the importance of Green Chemistry in the achievement of the ambitious goals of the current society, this special issue aims to demonstrate the potential of Green Chemistry in Europe. Hereby, it is my pleasure to invite the submission from all colleagues from universities, research centres, other institutions and industry focusing their activities in Europe who wish to demonstrate the importance of Green Chemistry.

Dr. Rafał M. Łukasik
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Europe
  • Sustainable development
  • Waste prevention
  • Renewable feedstock
  • Catalysis
  • Sustainable solvents

Published Papers (1 paper)

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Lipase-Catalyzed Production of Sorbitol Laurate in a “2-in-1” Deep Eutectic System: Factors Affecting the Synthesis and Scalability
Molecules 2021, 26(9), 2759; - 07 May 2021
Viewed by 533
Surfactants, such as glycolipids, are specialty compounds that can be encountered daily in cleaning agents, pharmaceuticals or even in food. Due to their wide range of applications and, more notably, their presence in hygiene products, the demand is continuously increasing worldwide. The established [...] Read more.
Surfactants, such as glycolipids, are specialty compounds that can be encountered daily in cleaning agents, pharmaceuticals or even in food. Due to their wide range of applications and, more notably, their presence in hygiene products, the demand is continuously increasing worldwide. The established chemical synthesis of glycolipids presents several disadvantages, such as lack of specificity and selectivity. Moreover, the solubility of polyols, such as sugars or sugar alcohols, in organic solvents is rather low. The enzymatic synthesis of these compounds is, however, possible in nearly water-free media using inexpensive and renewable building blocks. Using lipases, ester formation can be achieved under mild conditions. We propose, herein, a “2-in-1” system that overcomes solubility problems, as a Deep Eutectic System (DES) made of sorbitol and choline chloride replaces either a purely organic or aqueous medium. For the first time, 16 commercially available lipase formulations were compared, and the factors affecting the conversion were investigated to optimize this process, owing to a newly developed High-Performance Liquid Chromatography-Evaporative Light Scattering Detector (HPLC-ELSD) method for quantification. Thus, using 50 g/L of lipase formulation Novozym 435® at 50 °C, the optimized synthesis of sorbitol laurate (SL) allowed to achieve 28% molar conversion of 0.5 M of vinyl laurate to its sugar alcohol monoester when the DES contained 5 wt.% water. After 48h, the de novo synthesized glycolipid was separated from the media by liquid–liquid extraction, purified by flash-chromatography and characterized thoroughly by one- and two-dimensional Nuclear Magnetic Resonance (NMR) experiments combined to Mass Spectrometry (MS). In completion, we provide initial proof of scalability for this process. Using a 2.5 L stirred tank reactor (STR) allowed a batch production reaching 25 g/L in a highly viscous two-phase system. Full article
(This article belongs to the Special Issue Green Chemistry in Europe)
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