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Special Issue "Carbohydrate Recognition"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Chemical Biology".

Deadline for manuscript submissions: 15 September 2019

Special Issue Editor

Guest Editor
Prof. Dr. Ricardo Gutiérrez-Gallego

Department of Experimental and Health Sciences, Pompeu Fabra University, Barcelona Biomedical Research Park, 08003 Barcelona, Spain
Website | E-Mail
Interests: analytical chemistry; carbohydrate; biomolecular interactions; glycobiology; and protein/peptide pharmaceuticals

Special Issue Information

Dear Colleagues,

Carbohydrates as secondary gene events represent the mayor posttranslational modification. Ever since it was recognised as a relevant biological phenomenon numerous examples have been documented to certify the relevance of protein glycosylation. Yet, the indirect biosynthetic pathways, the numerous key intermediates and dependence on environmental parameters give rise to so-called microheterogeneity with multiple glycoforms for a single glycoprotein seriously hampering a straight-forward interpretation of structure-vs-function relationships. Nowadays, it is believed that the combination of a particular glycoform, i.e. the combination of a certain glycan on a particular protein backbone, at a particular timepoint is key to trigger a particular biological event. In order to continue contributing to the understanding of functional glycosylation it is crucial to continue developping novel tools based on the physico-chemical properties to address the site-specific glycosylation under biological circumstances. Likewise, novel strategies are needed to study biological interactions of particular glycoforms with the natural counterparts, capable of measuring under physiological conditions and finally, artificial inteligence will be required to enable understanding the occurrence of multiple biological conditions simultaneously. This issue shall focus on the latest advancements in the field of precise analysis of glycosylation, measurements of carbohydrate mediated interactions in a biological context and the development of machine learning algorithms to comprehensively grasp all continuously changing biofeatures.

Prof. Dr. Ricardo Gutiérrez-Gallego
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • global glycoscience
  • artificial intelligence
  • state-of-the art glycoanalytical tools
  • structure-function analysis

Published Papers

This special issue is now open for submission.
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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