Special Issue "Analysis of Drugs and Biologically Active Compounds Using Chromatographic and Electromigration Techniques"
Deadline for manuscript submissions: 31 October 2021.
Interests: electromigration techniques; bacteria characterization by capillary electrophoresis; wound dressing; zeta potential measurements; drug release from biomaterials
Special Issues and Collections in MDPI journals
Interests: green extraction and enrichment of bioactive compounds in natural products and their bioevaluation for metabolic and aging associated diseases such as diabetes, obesity, cancer, Alzheimer's and Parkinson's diseases
Analysis of biologically active substances is particularly important in the pharmaceutical and biomedical area. The chemical compounds which are present in the environment usually cause bad effects on health, the most serious ones being tumors and various mutations on a cellular level. Those compounds, from an analytical point of view, can serve the function of biomarkers, constituting measurable changes in the organism’s cells and biochemical processes occurring therein. The challenge of the 21st century is therefore finding effective and reliable methods of identification of biomarkers as well as understanding bodily functions, which occur in living organisms on a molecular level.
On the other hand, the detection and deterrence of abuse of performance-enhancing drugs in sport and also determination of the chemical composition of dietary supplements are important for maintaining a level playing field among athletes and for decreasing the threat to athletes’ health. Among the classes of prohibited substances (WADA prohibited list), three have given rise to the most recent analytical developments in the field: anabolic agents; peptide and protein hormones; and methods to increase oxygen delivery to tissues, including recombinant erythropoietin. Methods for anabolic agents, including designer steroids, have been enhanced through the use of chromatography coupled with mass spectrometry (GC/MS, LC/MS) and also electromigration techniques (CZE, MEKC). Incorporation of techniques such as flow cytometry, isoelectric focusing, and zeta potential measurements have supported the detection of blood doping.
The aim of this Special Issue is to cover topics related to the simulation determination of biologically active compounds (drugs, dietary supplements, biomarkers, doping substances) in biological samples and pharmaceutical products and the application of proposed analytical methods in medical diagnosis, antidoping research, and also pharmaceutical and biomedical area.
Real applications addressing dietary supplements, drugs, food, and biological and environmental systems are welcome. Researchers are cordially invited to contribute with original research and review articles to this Special Issue.
Assoc. Prof. Dr. Ewa Kłodzińska
Dr. Muhammad Ajmal Shah
Assistant Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Analytical chemistry
- Electromigration techniques
- Medical diagnosis
- Zeta potential measurements
- Determination of doping substances and dietary supplements