Dear Colleague,

The oxidation of alcohols to corresponding carbonyl compounds continues to be one of the key functional transformations in organic synthesis. Among the oxidizing agents, molecular oxygen used as a primary oxidant has attracted research attention and has been widely explored because aerobic oxidation is a highly environment friendly and atom-economical approach, with water as the only stoichiometric by-product. Several transition-metal-based catalysts have been used for the aerobic oxidation of alcohols. Organo catalysts, such as TEMPO (2,2,6,6-tetramethyl-1-piperidinyloxyl) and NHPI (N-hydroxyphthalimide), have also been explored and utilized in combination with the metal-based catalysts. However, the aerobic oxidation of alcohols sometimes faces problems associated with the use of gaseous oxygen, including a relatively low turn-over frequency and potential explosion. Recently, several reaction media and fields, such as ionic liquids, microbubbles, and micro flow reactors, have emerged to circumvent these issues. In this Special Issue, we welcome a wide range of research articles on recent advances in the aerobic oxidation of alcohols for application in unique fields.

Dr. Tsunehisa Hirashita
Guest Editor

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• Aerobic oxidation
• Alcohols
• Catalysts
• Unique reaction field
• Ionic liquids
• Microbubbles
• Micro-flow reactors.