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Flavonoids and Derivatives: One Health Approach

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 3392

Special Issue Editors


E-Mail Website
Guest Editor

E-Mail Website
Guest Editor Assistant
1. Posdoc CONAHCYT-Centro de Investigación en Alimentación y Desarrollo, A.C., Carretera a Eldorado Km. 5.5, Col. Campo El Diez, Culiacan CP 80110, Mexico
2. Laboratory of Functional Foods and Nutraceuticals, Centro de Investigación en Alimentación y Desarrollo, A.C., Carretera a Eldorado Km. 5.5, Col. Campo El Diez, Culiacan CP 80110, Mexico
Interests: food waste; bioprocess; bioactive compounds; optimization; plant biostimulants

E-Mail Website
Guest Editor Assistant
1. Posdoc CONAHCYT-Centro de Investigación en Alimentación y Desarrollo, A.C., Carretera a Eldorado Km. 5.5, Col. Campo El Diez, Culiacan CP 80110, Mexico
2. Laboratory of Functional Foods and Nutraceuticals, Centro de Investigación en Alimentación y Desarrollo, A.C., Carretera a Eldorado Km. 5.5, Col. Campo El Diez, Culiacan CP 80110, Mexico
Interests: flavonoids; medicinal plants; bioactive compounds; cell culture; cancer

Special Issue Information

Dear Colleagues,

The one health approach is a collaborative effort of multiple science professions to enhance people's health, domestic farm and food animals, plants, and our environment. Previous works have demonstrated that different bioactive compounds could be linked to maintaining optimal human health and improving animal, plant, and environmental health systems services. Among these, flavonoids are important in different matrices, such as food, plants, and microorganisms. In food and plants, these compounds can be induced by abiotic and biotic stresses as a defense mechanism. Also, different metabolic engineering tools have been developed to produce these compounds from microorganisms. Flavonoids and derivatives show multiple biological effects, such as antioxidant, antimutagenic, and anti-inflammatory, among other activities, as well as being related to improved animal performance and quality by using them as feed additives.

This Special Issue aims to provide a broad overview of flavonoids and derivatives as potential effects that contribute to the one health approach. Original research articles or reviews that discuss the potential of flavonoids and derivatives against optimal human and animal health, innovative methodologies for flavonoids and derivatives extraction from different sources, as well as other related articles, are welcome.

Prof. Dr. José Basilio Heredia
Guest Editor

Dr. Luis Angel Cabanillas-Bojórquez
Dr. Marilyn Shomara Criollo-Mendoza
Guest Editor Assistants

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • flavonoids
  • bioactive
  • health
  • nutraceutical
  • botanical
  • feed
  • microorganism

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Published Papers (1 paper)

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Review

19 pages, 1541 KiB  
Review
Protective, Anti-Inflammatory, and Anti-Aging Effects of Soy Isoflavones on Skin Cells: An Overview of In Vitro and In Vivo Studies
by Magdalena Wójciak, Piotr Drozdowski, Agnieszka Skalska-Kamińska, Martyna Zagórska-Dziok, Aleksandra Ziemlewska, Zofia Nizioł-Łukaszewska and Małgorzata Latalska
Molecules 2024, 29(23), 5790; https://doi.org/10.3390/molecules29235790 - 7 Dec 2024
Cited by 1 | Viewed by 3089
Abstract
Isoflavones are found in numerous plant species within the Leguminosae family; however, soy isoflavones are particularly significant in practice and have been extensively studied in recent years. The health-promoting potential of orally administered soy isoflavones is widely documented in the scientific literature, and [...] Read more.
Isoflavones are found in numerous plant species within the Leguminosae family; however, soy isoflavones are particularly significant in practice and have been extensively studied in recent years. The health-promoting potential of orally administered soy isoflavones is widely documented in the scientific literature, and many review articles have been developed to highlight their significance. However, it should be noted that soy-isoflavone-rich extracts and isolated soy isoflavones, such as genistein and daidzein, are also often applied topically as ingredients in many formulations, including face creams, tonics, and emulsions. New delivery systems are continuously being developed to enhance the skin permeability of isoflavones, thus improving their efficacy. In this context, their direct activity on skin cells is an important aspect of scientific research. The anti-inflammatory, protective, and antioxidant properties of isoflavones and soy extracts make them promising cosmetic ingredients with anti-aging potential because inflammation and the accumulation of reactive oxygen species (ROS) can lead to structural and functional changes in skin cells, accelerating the aging process. This review provides an overview of research on the impact of the application of soy isoflavone extract and soy-derived isoflavones on skin cells, with a focus on the documented molecular mechanisms underlying their effects. This study aims to offer essential insights to aid in the development of functional cosmetics and future clinical applications. Full article
(This article belongs to the Special Issue Flavonoids and Derivatives: One Health Approach)
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