Enzyme Immobilization and Its Application
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Bioorganic Chemistry".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 105
Special Issue Editor
Special Issue Information
Dear Colleagues,
Enzyme immobilization has evolved into a dynamic research field in recent years, integrating with advanced materials science, nanotechnology, and synthetic biology, going beyond classical applications. This Special Issue focuses on modern applications and innovative technological approaches to immobilized enzyme systems, rather than their traditional uses.
Current research encompasses the integration of advanced platforms such as nanostructured carriers, magnetic nanoparticles, metal–organic frameworks (MOFs), smart polymers, and 3D printing technologies into immobilization strategies. Furthermore, next-generation applications such as co-immobilization of multiple enzyme systems, artificial enzyme complexes, microfluidic systems, and biocatalytic reactor designs significantly increase process efficiency and selectivity.
In addition, the development of immobilization-compatible enzyme designs through protein engineering and directed evolution techniques paves the way for more robust and high-performance biocatalytic systems. Data science and AI-powered modeling approaches offer new horizons in optimizing immobilization parameters and system design.
This Special Issue aims to discuss the future role of immobilized enzyme systems in sustainable chemistry, biosensor technologies, biomedical applications, and industrial bioprocesses by promoting interdisciplinary approaches. It emphasizes that enzyme immobilization is not only a stabilization method but also a strategic tool in the design of intelligent and integrated biocatalytic platforms.
By bringing together interdisciplinary contributions, this issue aims to summarize emerging trends, identify current challenges, and define future research directions that will shape the next generation of immobilized enzyme technologies.
Prof. Dr. Dilek Alagoz
Guest Editor
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Keywords
- immobilization
- industrial enzymes
- kinetics
- proteins
- food
- enzyme stabilities
- nanostructures
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