Advances of Proteomics in Natural Product Chemistry
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 4885
Special Issue Editor
Special Issue Information
Dear Colleagues,
Natural products and their derivatives have been used in traditional medicine since the dawn of civilization for the treatment of a multitude of different pathologies, serving as a deliverer of chemical compounds with bioactive properties. The cells of many plants, animals, and microorganisms are rich sources of biologically active proteins that have been found to exhibit diverse functional properties, constituting an important category within nutraceuticals. Both the food and pharmaceutical industries have recently focused their efforts on the discovery of these types of proteins and peptides for the development of new food products and drugs aimed at improving the functioning of the human body and alleviating widespread health conditions, such as coronary heart disease, stroke, hypertension, cancer, obesity, or diabetes. Proteomic technology can help to correctly characterize these protein compounds through analysis strategies based on novel techniques and methodologies supported by mass spectrometry. The application of this technology, framed within the group known as “omic technologies”, also contributes to the detection of small molecules with bioactive potential through the interaction with their protein targets (chemical proteomics), thus improving the understanding of the mechanism of action of the drug and discovering possible therapeutic applications, as well as adverse side effects.
This Special Issue is dedicated to the study of natural products as a source of nutraceuticals through the application of proteomic technology with the aim of developing new food products and drugs in disease control. Topics include, but are not limited to, identification of biologically relevant compounds, application of proteomics to study the action of bioactive compounds, development of analytical methods focused on the characterization of active proteins and/or peptides, analysis of statistical and bioinformatic data derived from proteomic studies, and development of new foods and/or drugs. The application of proteomics in the study of natural bioactive compounds enables a deeper comprehension of their biological activities, promoting innovation and progress towards more natural foods and medicines, thus meeting market demand.
Dr. Rubén Agregán
Guest Editor
Manuscript Submission Information
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Keywords
- nutraceuticals
- bioactive compounds
- bioactive peptides
- novel drugs
- natural foods
- mass spectrometry
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