Multifunctional Conjugated Photosensitizers: Synthesis and Applications in Photodynamic and Phototherapy of Cancers
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 312
Special Issue Editors
Interests: organic chemistry; medicinal chemistry; antitumor drugs; antimitotic agents; photodynamic therapy; conjugated photosensitizers; targeted antitumor therapy
Interests: medicinal chemistry; photodynamic therapy; combined therapy; conjugated drugs; photosensitizers; photochemistry; targeted therapy for cancer; organic chemistry
Special Issue Information
Dear Colleagues,
At present, efficient synthetic protocols, along with well-understood photophysical mechanisms allow the creation of numerous important photosensitizing molecules which became irreplaceable tools in modern chemistry. That said, even more advanced and versatile materials can be created after the conjugation of photosensitizers with specific molecules or groups. Thus, incorporation of these counterparts can tune photosensitizers to specific needs. For example, rationally designed photocatalysts demonstrate superior photocatalytic properties, which can be even maintained in the living systems. Another important application is selective photodynamic (PDT) and photothermal therapies (PTT) of cancer diseases, where photosensitizers are routinely coupled with oncospecific vectors or other inhibitory drugs. In this regard, the therapy is usually enhanced through selective delivery or synergistic effects. For these materials, the utilization of stimuli-responsive linkers to release a photosensitizer in a particular cancer-related environment has also gained considerable attention.
This Special Issue plans to give an overview of the most recent advances in the synthesis and applications of conjugated photosensitizers in diverse areas, with a focus on their photosensitizing and antitumor properties. Research articles, perspectives, and reviews are welcome to be submitted to this issue.
Potential topics include, but are not limited to:
- Synthesis of photosensitizers;
- Conjugation of photosensitizers;
- Photodynamic therapy;
- Photothermal therapy;
- Photocatalysis in living systems;
- Selective delivery of photosensitizers;
- Multifunctional and stimuli-responsive photosensitizers.
Prof. Dr. Alexey Yu Fedorov
Guest Editor
Dr. Vasilii Otvagin
Guest Editor Assistant
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Keywords
- photodynamic therapy
- photothermal therapy
- photosensitizers
- conjugated photosensitizers
- targeted delivery
- photocatalysis
- multifunctional photosensitizers
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