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Structural Characteristics, Bioactivities and Mechanisms of Food-Derived Functional Compounds

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Food Chemistry".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 1

Special Issue Editors


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Guest Editor
School of Food Science and Engineering, Yangzhou University, Yangzhou 225127, China
Interests: polyphenols; polysaccharides; structural characterization; fresh-cut fruit and vegetable processing
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Guest Editor
College of Food Science and Engineering, Yangzhou University, Yangzhou 225127, China
Interests: polysaccharides; structural characterization; immunity; gut microbiota; intestinal health
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
College of Food Science and Engineering, Yangzhou University, Yangzhou 225127, China
Interests: bioactive polysaccharides; probiotics; metabolic diseases; gut microbiota

Special Issue Information

Dear Colleagues,

In recent years, food-derived functional compounds have attracted growing attention due to their diverse biological activities and significant potential in promoting human health and preventing chronic diseases. These compounds—including polyphenols, peptides, polysaccharides, flavonoids, carotenoids, and other bioactive molecules—are widely distributed in natural food sources and play essential roles in nutrition, metabolism, and disease modulation.

Understanding the structural characteristics, bioactivities, and underlying mechanisms of food-derived functional compounds is crucial for developing functional foods, nutraceuticals, and therapeutic agents. Recent advances in analytical chemistry, molecular biology, and food science have enabled researchers to elucidate the complex interactions between structure and function, providing insights into how these compounds exert antioxidant, anti-inflammatory, antimicrobial, and metabolic regulatory effects.

This Special Issue aims to present recent progress and innovative research on the isolation, characterization, biological activities, and action mechanisms of food-derived functional compounds. We welcome original research articles and reviews that contribute to the understanding of structure–activity relationships, metabolic pathways, and the practical applications of these bioactives in food and health-related industries.

The topics of interest include, but are not limited to, the following:

  • extraction, purification, and structural elucidation of food-derived functional compounds;
  • structure–activity relationship and functional characterization of bioactive food components;
  • mechanisms of antioxidant, anti-inflammatory, antimicrobial, or metabolic regulation activities;
  • applications of food-derived compounds in functional foods, nutraceuticals, and pharmaceuticals;
  • biotransformation, bioavailability, and metabolic fate of food bioactives;
  • advanced analytical and omics-based approaches for studying bioactive compounds from foods.

This Special Issue, “Structural Characteristics, Bioactivities and Mechanisms of Food-Derived Functional Compounds,” aims to provide a platform for interdisciplinary discussion and collaboration, fostering new insights into the role of food bioactives in health promotion and disease prevention.

Dr. Juan Kan
Dr. Dan Chen
Guest Editors

Dr. Chao Tang
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • food-derived bioactive compounds
  • structural characterization
  • structure–activity relationship
  • antioxidant activity
  • anti-inflammatory activity
  • antimicrobial mechanisms
  • functional foods
  • nutraceuticals
  • bioavailability
  • polysaccharides
  • polyphenols
  • peptides
  • flavonoids
  • carotenoids
  • biotransformation
  • molecular mechanisms

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Published Papers

This special issue is now open for submission.
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