Recent Progress in Synthesis and Bioactivity Studies of Heterocyclic Compounds
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 2185
Special Issue Editors
2. Key Laboratory of Nano-Carbon Modified Film Technology Engineering of Henan Province, Xinxiang 453000, China
Interests: cycloadditions; synthesis; heterocycles; biologically active compounds; synthetic methodology
Interests: synthesis; heterocycles; azoles; antibiofilm; sortase A; antimicrobial; anti-inflammatory; ADMETOX; molecular docking
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In this Special Issue, the aim is to report on recent advances in the use of heterocyclic scaffolds for the development of new bioactive molecules. Heterocyclic compounds play a remarkable role in the field of medicinal chemistry due to their correlation with various pharmacological properties. The molecules of most drugs used in therapy contain heterocyclic systems as active pharmacophores. At the same time, heterocycles could also influence other properties, such as lipophilicity, solubility, stability, and pharmacokinetics.
The multitude of methods available for the synthesis of various heterocycles offers many possibilities for the structural diversification and optimization of biologically active heterocyclic substances.
This Special Issue is dedicated but not limited to the presentation of results concerning the design, synthesis of novel heterocyclic compounds, and in silico/in vitro/in vivo assessment of their biological potential, mechanism of action, ADMETOX, etc.
Dr. Kaikai Wang
Dr. Smaranda Oniga
Guest Editors
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Keywords
- heterocycles
- bioactivity
- synthesis
- molecular docking
- mechanism of action
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