Characterization and Interaction of Nanoparticles in Biological Matrices

Dear Colleagues,

Nanoparticles show considerable potential for applications in many technological sectors, including pharmaceuticals, medical diagnostics, cosmetics, and food technology. Either purposefully or unintentionally, nanoparticles will eventually come into contact with physiological and biological matrices, such as intra- and extracellular fluids and blood plasma, which themselves are complex colloidal media with a multitude of components that readily interact with nanoparticles. Accordingly, the physicochemical properties of the particles, such as physical stability and chemical composition, may be affected, which impacts functionality and integrity and may result in unintended adverse reactions. Owing to such interactions, the behavior and the characterization of the particle system should not be decoupled from the given physiological/biological matrix.

This Special Issue aims to collect studies addressing the characterization of nanoparticles and interactions in such environments. Experimental, theoretical, and computational studies addressing physicochemical factors, such as particle concentration, size distribution, shape, chemical composition, surface chemistry, porosity, particle elasticity, mass density, and surface charge are most welcome.

Dr. Patricia Taladriz-Blanco
Dr. Sandor Balog
Guest Editors

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• bio-nano interfaces
• colloidal stability in biological/physiological fluids
• nanomedicine
• nanotoxicology
• particulate nanomaterials and nanoparticles
• physicochemical characterization