Synthesis, Characterization and Biological Evaluation of Metal Complexes
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Cross-Field Chemistry".
Deadline for manuscript submissions: 15 December 2025 | Viewed by 142
Special Issue Editors
Interests: chiral metallopharmaceuticals; chiral bioanalysis; illicit drugs
Interests: metallodrugs; metals in biology; pharmaceutical chemistry; chirality; anticancer and antimicrobial therapy
Special Issue Information
Dear Colleagues,
Since the first recognition of cisplatin as an effective anticancer agent, the interest in metal-based drug design has widely increased. Nowadays, bioactive metal complexes represent a promising and rapidly evolving area of pharmacotherapy. Metal complexes have demonstrated manifold biological activities, including antitumor, antimicrobial, anti-inflammatory, anti-infective, and antiparasitic effects. Metal complexes are also considered to be potential therapeutic agents for Alzheimer´s disease. Metallodrugs exhibit many unique properties as compared to purely organic substances, stemming from the presence of the metal atom and the variable arrangement of ligands around this central atom. The unique properties of metal complexes enable them to exert a variety of mechanisms in their interactions with living organisms.
This Special Issue is focused on new trends in design, synthesis, biological activities, and the target of action of metal complexes.
Dr. Jindra Valentová
Dr. Ladislav Habala
Prof. Dr. Jan Moncol
Guest Editors
Manuscript Submission Information
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Keywords
- metal complexes
- biological activity
- anticancer
- bioinorganic
- anti-inflammatory
- antimicrobial
- Alzheimer's disease
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