Recent Developments in Chromatographic Applications in Medicine
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: 15 August 2025 | Viewed by 41
Special Issue Editors
Interests: liquid chromatography; antioxidants; medicinal and pharmaceutical chemistry; drug design; lipophilicity; biomimetic chromatography; quantitative retention property relationships; quantitative structure activity relationships
Interests: liquid chromatography; separation methods/ sample pretreatment methods; chemometrics; pharmaceutical analysis; biomimetic chromatography; quantitative retention property relationships; electroanalysis
Special Issue Information
Dear Colleagues,
Chromatographic techniques are incredibly versatile, enabling the analysis of a wide range of complex samples. These include gas chromatography (GC), high-performance liquid chromatography (HPLC), and ion chromatography, among others. In recent years, the integration of chromatographic methods with modern detection systems has demonstrated remarkable capabilities for separation, identification, and quantification, which are essential for pharmaceutical analysis. These precise and sensitive analyses empower pharmaceutical scientists to assess purity, stability, and consistency during the stages of drug development and quality control. Furthermore, the development of biomimetic stationary phases has unfolded new perspectives in the simulation of biological processes in order to assess the pharmacokinetic and toxicological profile of candidate drugs and bioactive compounds.
This Special Issue, entitled "Recent Developments in Chromatographic Applications in Medicine", aims to present the latest advancements in the development and application of chromatographic techniques in medicinal chemistry. Topics include, but are not limited to, the screening, qualitative and quantitative analysis of active compounds, assessment of pharmacokinetic and toxicological profile of bioactive compounds, as well as the development of hyphenated methods.
Prof. Dr. Anna Tsantili-Kakoulidou
Dr. Fotios Tsopelas
Guest Editors
Manuscript Submission Information
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Keywords
- chromatography
- drug development
- quality control
- quantitative structure–retention relationships (QSRRs)
- quantitative retention–property relationships (QRPRs)
- chemometrics
- adsorption–distribution–metabolism–excretion–toxicity (ADMET properties)
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