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Environmental Pollutants and Oxidative Stress Chemistry

This special issue belongs to the section “Chemical Biology“.

Special Issue Information

Dear Colleagues,

The continuous release of environmental pollutants into aquatic and terrestrial ecosystems has generated growing concern about their ability to disrupt redox homeostasis and induce oxidative stress. At the molecular level, many contaminants—including pharmaceuticals, pesticides, metals, nanomaterials, and industrial by-products—trigger the overproduction of reactive oxygen and nitrogen species (ROS/RNS), leading to oxidative damage in lipids, proteins, and nucleic acids. These processes compromise organismal health and ecological balance while also providing valuable biomarkers for environmental monitoring.

This Special Issue "Environmental Pollutants and Oxidative Stress Chemistry" aims to highlight advances in the chemical and biochemical understanding of oxidative stress mechanisms induced by pollutant exposure. We welcome contributions exploring the generation, transformation, and fate of reactive species; the molecular pathways of redox imbalance; and the antioxidant defense systems that mitigate damage. Studies may include mechanistic insights, analytical approaches for ROS detection, oxidative stress biomarkers, antioxidant enzyme modulation, and chemical strategies for toxicity reduction.

By integrating redox chemistry, molecular toxicology, and environmental sciences, this Special Issue seeks to provide a platform for novel findings and critical perspectives that expand our understanding of pollutant-induced oxidative stress and guide future strategies for ecosystem protection and human health.

Prof. Dr. Leobardo Manuel Gomez-Olivan
Guest Editor

Dr. Gustavo Axel Elizalde-Velázquez
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • environmental pollutants
  • oxidative stress
  • reactive oxygen species (ROS)
  • antioxidant defense
  • redox chemistry

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Molecules - ISSN 1420-3049