Extraction of Plant-Derived Bioactives: Impacts on Human Health and Pharmacological Applications
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 493
Special Issue Editor
Interests: cytotoxicity in vitro; colon cancer; plant compounds activity; metastasis in vitro; 3D cell cultures Inflammation; cellular interactions
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The utilization of plant ingredients, which have demonstrated biological activity, is of increasing commercial importance in the treatment of patients and as a supportive therapy for classical therapeutic regimens. Full plant extracts and individual active ingredients isolated from them are of great importance. Full extracts demonstrate a rich palette of mutual interactions between individual substances, which show a synergistic effect, aimed at the patient's health. However, it is difficult to determine the mechanism of individual interactions. Conversely, isolated ingredients facilitate not only precise dosage determination but also the elucidation of their mechanism of action.
Plant-derived ingredients exert a multifaceted effect on organisms, operating at the molecular level by modulating signaling pathways within cells, at the genetic level, and also at the level of whole cells or tissues. By interacting with natural tissue mechanisms, they also engage with cellular and soluble components of the immune system. This is of significant importance for their pharmacodynamics and for recognizing them as factors that have a beneficial effect on health.
In this Special Issue, we invite you to present papers describing the isolation of substances from plant material, their identification, activity studies in both in vivo and in vitro systems, as well as the characterization of the mechanisms of this activity. We encourage submissions that evaluate the potential significance of the studied substances in terms of their practical usefulness and effectiveness in reducing undesirable phenomena at the cellular, tissue, and organism levels.
Prof. Dr. Roman Paduch
Guest Editor
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Keywords
- plant extracts
- bioactivity
- pharmacology
- human health
- natural compounds extraction
- natural compounds activity
- pharmacokinetics
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