Synthesis of Antiviral Compounds
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 6909
Special Issue Editor
Interests: pericyclic reactions; 1,3-dipolar cycloadditions; hetero diels-alder reactions; antivirals; catalysis; polymers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Viral infectious diseases continue to be a major health concern worldwide, causing relevant epidemiological, financial, and logistical implications, as we are experimenting in these months. The use of many conventional drugs is hampered by a lack of efficacy, the emergence of resistance, adverse effects, and high costs. Thus, new strategies and therapeutic alternatives are constantly needed. Nucleosides are fundamental building blocks of biological systems that show a wide range of biological activities. Consequently, extensive modifications have been made to both the heterocyclic base and the sugar moiety in order to avoid the drawbacks shown by nucleosides or analogues in certain applications, mainly due to enzymatic degradations. The design and synthesis of molecules for the fight against new aggressive and fatal diseases remain important challenges.
This Special Issue in Molecules aims to attract contributions on all the aspects concerning the synthesis through different strategies of classical nucleosides, carbocyclic nucleosides, and analogues. These results can be considered fully consistent if in vitro biological evaluations of the synthetized compounds are also reported. This will be the challenge to further explore the range of biological effects and potential applications as antivirals of brand-new compounds.
Prof. Dr. Paolo Quadrelli
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Nucleosides
- Nucleoside analogues
- Synthetic strategy
- Antivirals
- Biological evaluation
- Structure activity relationship
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.