Stress-Related Biomarkers: Analytical Methods and Their Applications
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: 30 March 2026 | Viewed by 232
Special Issue Editor
Interests: solid-phase microextraction; chromatography; advanced glycation end products; stress hormone; biomarker; heterocyclic amines; polycyclic aromatic hydrocarbons; LC–MS/MS analysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The main types of stress that affect human health include mental and physical stress, oxidative stress, glycation stress, and immune stress. Mental and physical stress manifests itself as a physical reaction via the autonomic nervous system, endocrine system (hormones), and immune system; if it becomes chronic, it can cause mental disorders and organic and functional disorders in various organs of the body. Oxidative stress occurs when the balance between active oxygen and the antioxidant system (antioxidant substances) and antioxidant enzymes is disrupted, causing various harmful oxidative disorders due to biological oxidation. Glycation stress is a phenomenon in which proteins in the body are degraded by non-enzymatic binding with excess sugar. When enough accumulation occurs in our cells and tissues, it causes a decline in function and is a factor in aging. Immunological stress is a micro-inflammation that occurs as a defense response to infection or injury; when it becomes chronic, it can also damage healthy tissue. In order to detect such stress responses in the body at an early stage and use them to diagnose and prevent disease, it is important to analyze biomarkers specific to each type of stress. Recently, there has been progress in the development of methods for detecting and quantifying useful biomarkers from various biological samples, including saliva, hair, nails, exhaled breath, and skin gas, as well as blood and urine. Moreover, there are high expectations for the development of new sample preparation and measurement methods.
This Special Issue will cover a wide range of topics related to efficient sample preparation, separation, and analysis methods such as chromatography and electrophoresis, as well as highly sensitive and selective analytical methods such as immunoassays and mass spectrometry, in order to analyze biomarkers for the various stresses mentioned above. It will also cover the applications of these biomarker analysis methods regarding the diagnosis and analysis of the mechanisms of various diseases related to lifestyle, fatigue, aging, and stress, as well as the analysis of stress factors.
I hope that this Special Issue, which will encompass the latest topics on stress-related biomarker analysis and examples of its application to various sample analyses, will be found interesting by scientists. I also hope that it will provide impetus for the birth of further ideas and new technologies, leading to the diagnosis and prevention of stress-related diseases.
Prof. Dr. Hiroyuki Kataoka
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biomarkers
- stress hormones
- advanced glycation end-products
- mental and physical stress
- oxidative stress
- glycation stress
- Immunological stress
- fatigue
- aging
- lifestyle-related diseases
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
