Old and New Challenges in Mycobacterium Infection Treatment
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".
Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 11014
Special Issue Editors
Interests: antimicrobial resistance; virology; molecular epidemiology; respiratory infections
Special Issue Information
Dear Colleagues,
The mycobacteria genus includes the greatest serial killers in the history of humankind, a lineage of skilled and devious pathogens, able to survive, multiply, and spread in an incredible variety of environmental niches, including humans.
Mycobacteria are extremely diverse organisms, able to act as species-specific pathogens responsible for major global health threats, or environmental saprophytes linked to a variety of largely neglected opportunistic clinical manifestations when the bacterial and human habitats overlap.
Our attempts toward their global eradication have, to date, been doomed to fail. Infections caused by mycobacteria are typically difficult to control, difficult to diagnose, and difficult to treat. The intrinsic resistance of these bacteria to many common antibiotics combines with an excellent ability to develop drug resistance following chromosome mutations, resulting in the generation of multidrug-resistant and pandrug-resistant variants, whose increasing global circulation is observed with growing concern.
This Special Issue aims to disseminate current research and knowledge on the most relevant microbiological, epidemiological, and clinical aspects related to the control of infection caused by tuberculosis-causing mycobacteria or non-tuberculous mycobacteria, with a particular focus on the generation and spread of drug resistance.
Dr. Valeria Cento
Prof. Stefano Aliberti
Guest Editors
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Keywords
- tuberculosis
- non-tuberculous mycobacteria
- drug resistance
- mycobacterial diagnosis
- pulmonary diseases
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