Special Issue "State-of-the-Art Gut Microbiota Research in Asia"

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".

Deadline for manuscript submissions: 31 July 2022 | Viewed by 1153

Special Issue Editors

Dr. Ryo Inoue
E-Mail Website
Guest Editor
Department of Applied Biological Sciences, Faculty of Agriculture, Setsunan University, Hirakata 573-0707, Japan
Interests: gut microbiota; pig; colostrum; pathogen metagenomics; mucosal immunology
Dr. Saori Kashiwagi
E-Mail Website
Guest Editor
Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto-shi 602-8566, Kyoto, Japan
Interests: gut microbiota; gut disease

Special Issue Information

Dear Colleagues,

As we know, our gut microbiota is diverse among individuals and each has its own unique profile. It is because of the difference in genetic origin, habit, lifestyle, cuisine, and so on. These factors depend on regional and racial diversity. Asia is one of the largest and most populous continents, including unique and various characteristics; thus, gut microbiota in Asia might also be characteristic.

The aim of this Special Issue is to spotlight the gut microbiota research in Asia, including the effect of Asian cuisine/ingredients to structural/functional difference of gut microbiota, metabolic interaction within bacteria or the host immune response, and pathogenicity in inflammatory disease. We invite colleagues to contribute original research articles or reviews related to their research. Topics include, but are not limited to:

  • Structure and function of the microbiota
  • Microbial community genetics, transcriptomics, proteomics and metabolomics
  • Interaction within the microbiota
  • Metabolic interaction with the host
  • Inflammatory diseases
  • Interaction with the immune system
  • Microbial biodegradation of nutrients and xenobiotics
  • Microbial ecology
  • Microbial functions in the different habitats within the gut
  • Metabolic flux analysis
  • Analysis of functionalities by stable isotope probing (DNA, RNA and protein)
  • Model systems for studying microbiome biology
  • Novel technologies for the analysis of structure and function of the microbiota

Dr. Ryo Inoue
Dr. Saori Kashiwagi
Guest Editors

Manuscript Submission Information

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Published Papers (1 paper)

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Research

Article
Typing of the Gut Microbiota Community in Japanese Subjects
Microorganisms 2022, 10(3), 664; https://doi.org/10.3390/microorganisms10030664 - 20 Mar 2022
Viewed by 883
Abstract
Gut microbiota are involved in both host health and disease and can be stratified based on bacteriological composition. However, gut microbiota clustering data are limited for Asians. In this study, fecal microbiota of 1803 Japanese subjects, including 283 healthy individuals, were analyzed by [...] Read more.
Gut microbiota are involved in both host health and disease and can be stratified based on bacteriological composition. However, gut microbiota clustering data are limited for Asians. In this study, fecal microbiota of 1803 Japanese subjects, including 283 healthy individuals, were analyzed by 16S rRNA sequencing and clustered using two models. The association of various diseases with each community type was also assessed. Five and fifteen communities were identified using partitioning around medoids (PAM) and the Dirichlet multinominal mixtures model, respectively. Bacteria exhibiting characteristically high abundance among the PAM-identified types were of the family Ruminococcaceae (Type A) and genera Bacteroides, Blautia, and Faecalibacterium (Type B); Bacteroides, Fusobacterium, and Proteus (Type C); and Bifidobacterium (Type D), and Prevotella (Type E). The most noteworthy community found in the Japanese subjects was the Bifidobacterium-rich community. The odds ratio based on type E, which had the largest population of healthy subjects, revealed that other types (especially types A, C, and D) were highly associated with various diseases, including inflammatory bowel disease, functional gastrointestinal disorder, and lifestyle-related diseases. Gut microbiota community typing reproducibly identified organisms that may represent enterotypes peculiar to Japanese individuals and that are partly different from those of indivuals from Western countries. Full article
(This article belongs to the Special Issue State-of-the-Art Gut Microbiota Research in Asia)
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