Special Issue "Gut Bacteria-Mucus Interaction"
Deadline for manuscript submissions: closed (31 March 2018)
Dr. Nathalie Juge
Quadram Institute Bioscience, The Gut Health and Food Safety Institute Strategic Programme, Norwich Research Park, Norwich NR4 7UA, UK
Website | E-Mail
Interests: gut microbiota; mucin glycosylation; gastrointestinal mucus; carbohydrate recognition; adhesins; lectins; mucin degradation; mucus adhesion
The mucus layer covering the gastrointestinal tract plays a key role in maintaining a homeostatic relationship with our gut microbiota. The large intestine, which is home to most microbial species constituting the gut microbiota, is lined by a bi-layer of mucus. The outer layer providies a habitat for bacteria, whereas the inner layer maintains them at a safe distance from the epithelial surface. The terminal mucin O-glycans have been proposed to serve as attachment sites and metabolic substrates to the gut commensal bacteria, which have adapted to the mucosal environment. However, the molecular mechanisms underpinning gut bacteria-mucin glycan interactions remain poorly defined. Exploring the molecular basis of mucin adhesion and degradation of mucin glycans by predominant species of the gut microbiota is particularly important for the design of refined strategies to restore gut health. This issue will publish papers on the mechanistic aspects of gut bacteria-mucus interactions.
Dr. Nathalie Juge
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- gut microbiota
- mucin glycosylation
- gastrointestinal mucus
- carbohydrate recognition
- mucin degradation
- mucus adhesion