Candida spp. and Their Virulence
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".
Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 9387
Special Issue Editor
Interests: Candida albicans; Endodontic irrigants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The genus Candida includes several species able to colonize and proliferate in different habitats. Although Candida albicans continues to be the most common agent of human infection, other species have emerged as important pathogens, such as Candida glabrata or Candida parapsilosis, and, lately, Candida auris. The plasticity of the biological traits of Candida spp. relies on their association to microbiotas in a commensal way of life. However, the major concern about these fungi is when they shift into aggressive agents of infection, especially in the susceptible human host, and when resistant to the available therapeutics. The virulence with which Candida species cause damage to the host is strongly linked to the characteristics of each Candida species/strain, their ability to survive to deleterious environments, and the armamentarium to escape or subvert the immune system. Irrespective of their virulence, the engagement of the immune response by these pathobionts can be a major contributor for immune-inflammatory diseases.
This Special Issue aims to detail the characteristics of Candida spp., their interaction with the immune system, and the consequences of this interaction to human health.
Prof. Teresa Gonçalves
Guest Editor
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Keywords
- Candida spp.
- biology of Candida
- virulence factors
- pathogenesis
- mycobiota
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