The Role of Microbiota in Cancer Development and Therapy
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 6
Special Issue Editor
Interests: cancers; viral infection; emerging pathogens; diagnosis; treatment
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue aims to explore the complex and increasingly recognized role of the human microbiota in cancer development, progression, and treatment response. Microbial communities residing in the gut, oral cavity, skin, and other body sites have profound effects on host immunity, metabolism, and inflammation—key factors influencing tumorigenesis. Recent advances highlight the microbiota’s dual role: certain microbial populations contribute to carcinogenesis, while others exhibit protective or therapeutic potential.
Areas of interest include, but are not limited to, the following:
- Mechanistic links between dysbiosis and cancer initiation or progression;
- The impact of microbiota on tumor microenvironment and immune modulation;
- Microbial biomarkers for cancer risk, prognosis, and therapy response;
- The influence of microbiota on chemotherapy, radiotherapy, and immunotherapy efficacy and toxicity;
- Microbiome-targeted interventions (e.g., probiotics, antibiotics, fecal microbiota transplantation) in cancer prevention and treatment;
- Interactions between diet, microbiota, and cancer;
By integrating microbiology, oncology, immunology, and systems biology, this Special Issue aims to deepen our understanding of how modulating the microbiome may unlock novel strategies for cancer prevention, diagnosis, and personalized therapy.
Dr. Shengxi Chen
Guest Editor
Manuscript Submission Information
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Keywords
- microbiota
- microbiome
- cancer
- tumorigenesis
- dysbiosis
- inflammation
- immune modulation
- gut microbiota
- tumor microenvironment
- cancer therapy
- microbial metabolites
- probiotics
- cancer prevention
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