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Microorganisms
Special Issues
Gut Microbiota: Its Role in Liver Disease and Atherosclerosis
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Gut Microbiota: Its Role in Liver Disease and Atherosclerosis

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".

Deadline for manuscript submissions: closed (20 April 2022) | Viewed by 3535

Special Issue Editor

Prof. Dr. Daniel Florin Lighezan

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Guest Editor
Faculty of Medicine, “Victor Babes” University of Medicine and Pharmacy Timisoara, Square Eftimie Murgu No. 2, 30041 Timisoara, Romania
Interests: cardiology; internal medicine; heart failure; atherosclerosis; arterial hypertension
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The rising interest in gut microbiota in the last decade is due to increased knowledge in this area and also to technological advancements. The human gastrointestinal tract represents the host of more than 2000 different species of bacteria, archaea and eukaryotic microbes that co-evolved with the host over thousands of years, contributing to metabolic functions, protecting against pathogens, educating the immune system, and, through these basic functions, directly or indirectly affecting most of the physiologic functions. The aim and scope of the Special Issue is to present the latest knowledge on gut microbiota influence on liver disease and atherosclerosis. We also will try to focus on microbiota as a therapeutic target in the prevention of cardiovascular diseases and the beneficial mechanisms of probiotic administration related to cardiovascular risks.

Prof. Dr. Daniel Florin Lighezan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gut microbiota
  • microbiome
  • liver disease
  • atherosclerosis
  • cardiovascular disease

Published Papers (1 paper)

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Review

30 pages, 1058 KiB  
Review
Trust Your Gut: The Association of Gut Microbiota and Liver Disease
by Ridda Manzoor, Weshah Ahmed, Nariman Afify, Mashal Memon, Maryam Yasin, Hamda Memon, Mohammad Rustom, Mohannad Al Akeel and Noora Alhajri
Microorganisms 2022, 10(5), 1045; https://doi.org/10.3390/microorganisms10051045 - 18 May 2022
Cited by 20 | Viewed by 3208
Abstract
The gut microbiota composition is important for nutrient metabolism, mucosal barrier function, immunomodulation, and defense against pathogens. Alterations in the gut microbiome can disturb the gut ecosystem. These changes may lead to the loss of beneficial bacteria or an increase in potentially pathogenic [...] Read more.
The gut microbiota composition is important for nutrient metabolism, mucosal barrier function, immunomodulation, and defense against pathogens. Alterations in the gut microbiome can disturb the gut ecosystem. These changes may lead to the loss of beneficial bacteria or an increase in potentially pathogenic bacteria. Furthermore, these have been shown to contribute to the pathophysiology of gastrointestinal and extra-intestinal diseases. Pathologies of the liver, such as non-alcoholic liver disease, alcoholic liver disease, cirrhosis, hepatocellular carcinoma, autoimmune hepatitis, viral hepatitis, and primary sclerosing cholangitis have all been linked to changes in the gut microbiome composition. There is substantial evidence that links gut dysbiosis to the progression and complications of these pathologies. This review article aimed to describe the changes seen in the gut microbiome in liver diseases and the association between gut dysbiosis and liver disease, and finally, explore treatment options that may improve gut dysbiosis in patients with liver disease. Full article
(This article belongs to the Special Issue Gut Microbiota: Its Role in Liver Disease and Atherosclerosis)
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