Effect of Bacterial Biofilms Colonization on Oral Health and Therapy 2.0

Dear Colleagues,

A bacterial biofilm is a common ecological community, where bacteria are held together by an extracellular matrix, and use different mechanisms to align their activity within the community and to achieve complex multi-cellular activities. Biofilms enable bacteria to attach more firmly to their hosts and to have better access to nutrients. When compared to the planktonic (free-living) state, bacteria in biofilms are more protected from environmental insults, antibiotics, and the immune system. Biofilm colonization represents most of the microbial infections in the human body including in the oral cavity, where biofilms are the main source of many oral diseases, such as dental abscesses, periodontal diseases, and dental caries. These colonized oral biofilms pose a significant clinical challenge as they may resist common therapies and produce persistent infections.

The aims of the Special Issue are to present up-to-date evidence-based data regarding the colonization of bacterial biofilms in the different niches of the oral cavity and their involvement in oral diseases, and to present novel therapeutic approaches to overcome these persistent infections.

Dr. Eyal Rosen
Guest Editor

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• biofilm
• bacterial colonization
• oral microbiota
• bacterial resistance
• persistent infection
• endodontic biofilms
• periodontal biofilms
• prosthodontics and oral biofilms
• novel methods to eradicate oral biofilms