Veterinary Microbiology and Immunology

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Veterinary Microbiology".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 125

Special Issue Editor


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Guest Editor
College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China
Interests: animal infectious disease; pathogenesis; host-pathogen interactions

Special Issue Information

Dear Colleagues,

This Special Issue provides a platform for the dissemination of knowledge on domesticated and wild animal microorganisms (bacteria, fungi, viruses) in terms of pathogenicity and diagnosis, disease prevention and treatment, epidemiological analysis, pathology, immunity, and vaccine development. It is intended for scientists who conduct research on wild and domesticated animals, veterinarians, conservation biologists, and immunological and vaccine scientists.

Dr. Qihui Luo
Guest Editor

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Keywords

  • animal
  • metabolic diseases
  • infectious diseases
  • pathogenesis
  • host-pathogen interactions
  • microbiome

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Published Papers (1 paper)

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Research

13 pages, 3095 KiB  
Article
Uterine Microbiota Composition in Dairy Cows with Different Vaginal Discharge Scores: Suggesting Caviibacter as a Potential Pathogen in Mild Purulent Metritis
by Xiaolei He, Jiajia Wang, Lin Jiang, Xinyu Wang, Yuxing Wang, Yang Liu, Yanping Cheng, Fei Xu and Xiubo Li
Microorganisms 2025, 13(8), 1728; https://doi.org/10.3390/microorganisms13081728 - 24 Jul 2025
Abstract
The uterine microbiota plays a crucial role in maintaining postpartum reproductive health in dairy cows, and its dysregulation is closely associated with uterine diseases. Vaginal discharge characteristics serve as important clinical indicators for assessing uterine status and guiding clinical decision-making. This study employed [...] Read more.
The uterine microbiota plays a crucial role in maintaining postpartum reproductive health in dairy cows, and its dysregulation is closely associated with uterine diseases. Vaginal discharge characteristics serve as important clinical indicators for assessing uterine status and guiding clinical decision-making. This study employed 16S rRNA gene sequencing to analyze uterine microbial diversity in cows with different discharge types. Results revealed significant microbial shifts associated with discharge severity. Notably, Caviibacter was highly enriched (up to 60.25%) in cows with mildly purulent discharge (<50%), suggesting its potential role in early-stage endometritis. In contrast, Fusobacterium and Helcococcus dominated when purulent discharge exceeded 50%, while Bacteroides, Porphyromonas, and Peptostreptococcus prevailed in cows with malodorous or discolored secretions, indicating severe inflammation. This study extends previous findings by uncovering stage-specific microbial transitions and proposing Caviibacter as a potential early biomarker of endometritis. These insights support early diagnosis and targeted interventions, contributing to improved reproductive management and sustainable dairy farming. Full article
(This article belongs to the Special Issue Veterinary Microbiology and Immunology)
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