Biosynthesis of Plant-Derived Bioactive Components by Photosynthetic Microorganisms

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".

Deadline for manuscript submissions: 15 December 2024 | Viewed by 657

Special Issue Editors

College of Forestry, Beijing Forestry University, Beijing 100083, China
Interests: cyanobacteria; synthetic biology; plant-derived bioactives; molecular toolkit generate; protein homeostasis and stress response in cyanobacteria
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Guest Editor
Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China
Interests: water quality; water pollution; aquatic organism; aquatic ecosystem; bioremediation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Plant-derived bioactive compounds, including fatty acids, terpenoids, flavonoids, and alkonids, have versatile bioactivities used either for biopesticides in agriculture or health-promoting benefits in the food and pharmaceutical industries. However, the low synthesis amount of these compounds from plants can hardly satisfy commercial demands, and the dependence of these compounds on plants could also lead to detrimental ecological effects. Photosynthetic bacteria, such as cyanobacteria, harbor several inherited merits that make them excellent microbial cell factories. They can directly absorb CO2 from the atmosphere and store it in organic compounds with high efficiency owing to their CO2 concentrating mechanism, which offers a thorough strategy to neutralize carbon footprints. The photosynthesis process of photosynthetic bacteria supplies versatile substrates for plant secondary metabolite biosynthesis, and the absence of subcellular organelles and compartments to separate various metabolites provides the opportunity to think outside the box and design some biosynthetic pathways that are more challenging to achieve in higher plants or other eukaryotic cells. Of course, more challenges need to be overcome, and one of the most significant issues is how to improve target productivity. Strategies such as carbon fixation enhancement, carbon flow optimization, and novel biosynthetic pathways are highly appreciated in the community. This Special Issue of Plants will highlight the process of all relevant studies and cover a broad range from biodesign logic, biocompound synthesis feasibility, and production improvements, with the intent of providing an index and encouraging more scientists to become involved in the relevant research area.

You may choose our Joint Special Issue in Plants.

Dr. Haojie Jin
Prof. Dr. Yonghong Bi
Guest Editors

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  • photosynthetic bacteria
  • biosynthsis
  • bioactive compounds
  • metabolic engineering

Published Papers (1 paper)

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16 pages, 1379 KiB  
A Study on the Effect of Various Media and the Supplementation of Organic Compounds on the Enhanced Production of Astaxanthin from Haematococcus lacustris (Girod—Chantrans) Rostafinski (Chlorophyta)
by Vijay Rayamajhi, Yunji An, Huijeong Byeon, Jihyun Lee, Taesoo Kim, AhJung Choi, JongDae Lee, KwangSoo Lee, ChulHyun Kim, HyunWoung Shin and SangMok Jung
Microorganisms 2024, 12(6), 1040; - 21 May 2024
Viewed by 525
Natural astaxanthin is in high demand due to its multiple health benefits. The microalga Haematococcus lacustris has been used for the commercial production of astaxanthin. In this study, we investigated the effects of six different media with and without a nitrogen source and [...] Read more.
Natural astaxanthin is in high demand due to its multiple health benefits. The microalga Haematococcus lacustris has been used for the commercial production of astaxanthin. In this study, we investigated the effects of six different media with and without a nitrogen source and supplementation with nine organic compounds on the growth and astaxanthin accumulation of H. lacustris. The highest astaxanthin contents were observed in cultures of H. lacustris in Jaworski’s medium (JM), with a level of 9.099 mg/L in JM with a nitrogen source supplemented with leucine (0.65 g/L) and of 20.484 mg/L in JM without a nitrogen source supplemented with sodium glutamate (0.325 g/L). Six of the nine organic compounds examined (leucine, lysine, alanine, sodium glutamate, glutamine, and cellulose) enhanced the production of astaxanthin in H. lacustris, while malic acid, benzoic acid, and maltose showed no beneficial effects. Full article
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