Mycobacterium tuberculosis: Diagnostics, Drug Resistance and Molecular Epidemiology
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 2174
Special Issue Editor
Interests: tuberculosis diagnostics; drug-resistant tuberculosis; public health
Special Issue Information
Dear Colleagues,
Mycobacterium tuberculosis remains a major global health threat, responsible for significant morbidity and mortality, particularly in low- and middle-income countries. The emergence and spread of drug-resistant forms, including multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR-TB), pose serious challenges to TB elimination efforts. Timely and accurate diagnosis, coupled with reliable detection of drug resistance, is essential to guide appropriate therapy and reduce transmission.
In recent years, advances in molecular diagnostics—such as line probe assays, real-time PCR platforms, and whole-genome sequencing—have transformed TB detection and drug susceptibility testing, offering faster and more precise results compared to conventional methods. Furthermore, molecular epidemiology studies provide critical insights into transmission dynamics, outbreaks, and the evolution of resistance-associated mutations.
This Special Issue aims to gather original research and reviews focusing on innovative diagnostic approaches, mechanisms of drug resistance, molecular surveillance, and epidemiological studies of M. tuberculosis. Contributions addressing challenges in implementation, novel biomarkers, and applications of genomic technologies in clinical or public health settings are particularly welcome.
I look forward to hearing from you.
Dr. Juliana Maíra Watanabe Pinhata
Guest Editor
Manuscript Submission Information
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Keywords
- Mycobacterium tuberculosis
- tuberculosis diagnostics
- drug-resistant tuberculosis
- multidrug-resistant tuberculosis (MDR-TB)
- molecular epidemiology
- whole-genome sequencing
- tuberculosis molecular typing
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