Microfluidics and Mass Spectrometry
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".
Deadline for manuscript submissions: closed (1 December 2020) | Viewed by 143
Special Issue Editors
Interests: microfluidics; mass spectrometry; drug metabolism; microreactors; polymer microfabrication
Interests: microfluidics; 3D printing; rapid prototyping; mass spectrometry; microfabrication
Special Issue Information
Dear Colleagues,
The combination of microfluidics and mass spectrometry (MS) is one of the most powerful analytical concepts due to its many advantages, including (but not limited to) the high speed of microfluidic separation systems and the substantially reduced reagent consumption of microfluidic sample preparation systems supplemented with the high sensitivity and selectivity of MS detection. The combination of microfluidics and MS seems particularly promising toward non-targeted bioanalysis, e.g., in proteomics and metabolomics research. Since the late 1990s, microfabrication has been widely exploited for the fabrication of not only microfluidic sample preparation and separation devices but also of miniaturized ion sources and sample support plates for desorption/ionization MS. Significant effort has gone to materials characterization in search of new approaches that simultaneously enable versatile microfabrication possibilities (e.g., integration of an on-chip emitter tip) and good biocompatibility and physico-chemical stability (e.g., toward organic solvents common to MS).
This Special Issue seeks to showcase research papers, short communications, and review articles that highlight recent developments among, e.g., hyphenated separation techniques (including two-dimensional microfluidic separation systems) as well as extensions toward MS detection of paper microfluidic, droplet microfluidic, and/or microfluidic single-cell assays. Papers reporting progress in ever-evolving microchip fabrication approaches feasible for increasing the degree of integration are also welcome.
Dr. Tiina Sikanen
Dr. Markus Haapala
Guest Editors
Manuscript Submission Information
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Keywords
- mass spectrometry
- miniaturized ion sources
- electrospray/nanospray ionization
- microfluidic separation systems
- microfluidic sample preparation systems
- micro total analysis systems
- paper microfluidics
- droplet microfluidics
- metabolomics
- proteomics
- bioanalysis
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