Gut Microbiome in Disease Pathogenesis
A special issue of Microbiology Research (ISSN 2036-7481). This special issue belongs to the section "Medical and Veterinary Microbiology".
Deadline for manuscript submissions: 31 March 2027 | Viewed by 213
Editors
Interests: diabetes; immunity; inflammation; atherosclerosis; chronic kidney disease; preeclampsia
Interests: immunity; endocrine; chronic diseases; inflammatory bowel diesel; diabetes mellitus; preeclampsia
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The gut microbiome plays a central role in human physiology through its effects on metabolism, immune regulation, epithelial barrier integrity, and resistance to pathogens. Alterations in microbial composition and function, commonly referred to as dysbiosis, have been associated with a wide range of disorders, including inflammatory, metabolic, autoimmune, infectious, neurological, and neoplastic diseases. However, the mechanisms through which microbial communities contribute to disease initiation, progression, and treatment response remain incompletely understood.
This Special Issue, "Gut Microbiome in Disease Pathogenesis", will present current research on the molecular, cellular, and immunological mechanisms linking the intestinal microbiota to human disease. Particular attention will be given to host–microbiome interactions, mucosal immunity, microbial metabolites, intestinal barrier dysfunction, chronic inflammation, and microbiome-mediated modulation of systemic immune responses.
Relevant topics include the following:
- Gut dysbiosis in inflammatory and autoimmune diseases;
- Microbiome–immune system crosstalk;
- Mucosal immunology and intestinal barrier function;
- Microbial metabolites and immune regulation;
- Gut microbiome involvement in metabolic, neurological, infectious, and malignant diseases;
- Multi-omics approaches for studying host–microbiome interactions;
- Microbiome biomarkers for diagnosis, prognosis, and treatment response;
- Probiotics, prebiotics, postbiotics, dietary interventions, and microbiota-based therapies;
- Personalized and precision medicine strategies targeting the gut microbiome.
Dr. Mohamed-Zakaria Assani
Prof. Dr. Mihail Virgil Boldeanu
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gut microbiota
- dysbiosis
- host–microbiome interactions
- mucosal immunology
- immune modulation
- microbiome–immune crosstalk
- microbial metabolites
- inflammation
- disease pathogenesis
- microbiome-based therapeutics
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