Special Issue "Cell-Based Microarrays"
A special issue of Microarrays (ISSN 2076-3905).
Deadline for manuscript submissions: closed (31 March 2016).
Interests: HCS; HTS; automation; cellular assays; gene perturbation and observation; data mining; miniaturization; automated correlative light microscopy
In 2001, Ziauddin and Sabatini introduced the first cell-based microarray as a microarray-driven gene expression system. In the original set-up, different cDNA vectors were printed on a glass support. After, cells were grown over the whole surface, thus resulting in a cellular response in the printed locations. Subsequent publications have matched the technique to diverse applications involving RNAi and compounds. The potential of this method for performing gene function analysis and for identifying novel therapeutic targets and agents has now been clearly shown. Thus, cell-based microarrays have become an appreciated tool in basic research and drug discovery.
The advancement of miniaturized cell-based microarrays offers a multitude of advantages that are out of reach for conventional macroscale cell screening methods, which use microtiter plates. Amongst other advantages, the small dimensions of typical cell-based microarrays greatly reduce consumables, cell and drug consumption; this advantage is particularly important for rare cell analysis and cost reductions.
In this Special Issue, we invite material regarding new developments, technological advancements, and applications involving cell-based microarrays. Information about the new developments associated with data analysis and data mining is also critical in the area of cell-based microarrays.
Dr. Holger Erfle
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microarrays is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 350 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cell-based microarrays
- reverse transfection
- gene perturbation
- data analysis
- cell types
- cellular assays