Changes in Body Composition (Bone, Muscle, Adipose Tissue) with Age and Accompanying Biomarkers for Each Tissue
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 112
Special Issue Editor
Interests: metabolism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Although body composition (including bone, muscle, adipose tissue, etc.) plays a critical role in health and may be an underlying condition in many chronic diseases, its changes with age have not been comprehensively studied. It was assumed that, in women, decreases in bone and muscle and increases in fat tissue occur with menopause, whereas there was no specific timing for body composition changes in men. The relatively newly identified syndrome known as oateosarcopenic adiposity (OSA) denotes the simultaneous deterioration of bone (osteopenia/osteoporosis) and muscle (sarcopenia/dynapenia) with the increased presence of body fat, either as overtly related to overweight/obesity or redistributed and/or infiltrated fat. With this syndrome in mind, the purpose of this Special Issue is to bring more insight into body composition changes with age or the metabolic nature of each of these tissues. We aim to eventually obtain a better understanding of OSA by investigating the following:
- The relationship between chronological age and body composition (bone, muscle, and/or fat), highlighting the spikes at which these components peak or nadir in generally healthy men and women.
- The biomarkers for each tissue (bone, muscle, and/or adipose) or their combinations that may indicate existing impairments in each tissue and/or ultimately the presence of OSA.
Dr. Jasminka Ilich
Guest Editor
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Keywords
- bone
- muscle
- adipose tissue
- osteosarcopenic adiposity
- nutrition, physical activity, and lifestyle habits influencing body composition
- inflammatory markers
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