Multi-Omics for Identifying Biosynthetic Pathways of Active Components in Medicinal Plants

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Plant Metabolism".

Deadline for manuscript submissions: 30 April 2026 | Viewed by 9

Special Issue Editors

Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450000, China
Interests: transcriptomics; metabolomics; molecular biology; biochemistry; bio-activity; anti-cancer; biosynthesis

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Guest Editor
Bavarian NMR Center—Structural Membrane Biochemistry, Department of Chemistry, Technical University of Munich, 85748 Garching, Germany
Interests: plant metabolites; metabolism; stable isotopes
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Special Issue Information

Dear Colleagues,

Medicinal plants are a major source of natural products that have long played a crucial role in disease treatment and health promotion. Natural products are characterized by structural diversity, broad biological activities, and relatively high safety and efficacy, making them highly valuable for drug discovery and clinical applications. However, medicinal plant resources are often scarce, their growth is slow, and they are easily affected by environmental factors. In addition, the content of natural products in plants is usually very low, and the efficiency of extraction and isolation remains limited. These challenges have greatly restricted the development and application of bioactive compounds from medicinal plants. In recent years, advances in omics technologies, metabolic engineering, and synthetic biology have facilitated the elucidation of biosynthetic pathways of many natural products, opening new opportunities for scalable production through microbial or cellular chassis. This Special Issue aims to highlight the latest progress in natural products from medicinal plants, with a focus on biosynthetic pathway elucidation, identification and functional characterization of key genes, and applications of synthetic biology for efficient production. We welcome original research articles and reviews in related fields to provide new insights and perspectives for both fundamental research and industrial translation of medicinal plant natural products.

Dr. Lihang Xie
Prof. Dr. Wolfgang Eisenreich
Guest Editors

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Keywords

  • multi-omics
  • medicinal plants
  • bioactive natural products
  • biosynthetic pathway
  • metabolic engineering
  • microbial cell factories

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Published Papers

This special issue is now open for submission.
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