Effects of Various Exercise Methods on Metabolic Health

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".

Deadline for manuscript submissions: 28 November 2025 | Viewed by 565

Special Issue Editors


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Guest Editor
1. Department of Sports Medicine and Science, Graduate School, Konkuk University, Seoul 05029, Republic of Korea
2. Physical Activity and Performance Institute, Konkuk University, Seoul 05029, Republic of Korea
Interests: altitude training; hypoxic conditioning; exercise physiology and intervention; athletic performance; obesity; hypertension; metabolic syndrome; sarcopenia; mental disorder; mild cognitive impairment
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Department of Senior Exercise Prescription, Dongseo University, Busan 47011, Republic of Korea
Interests: exercise physiology; exercise prescription; environmental physiology senior exercise prescription; metabolism-related exercise programs; sar-copenia; mild cognitive impairment; walking exercise

Special Issue Information

Dear Colleauges,

Metabolic health is a crucial component of overall well-being as it influences the risk of chronic diseases, such as obesity, type 2 diabetes, cardiovascular diseases, and metabolic syndrome. While diet and nutrition play fundamental roles in metabolic regulation, physical activity and structured exercise interventions are widely recognized as key modulators of metabolic pathways. Different exercise modalities—ranging from aerobic and resistance training to high-intensity interval training (HIIT), whole-body electromyostimulation (WB-EMS), and neuromuscular rehabilitation programs—offer diverse benefits regarding glucose homeostasis, lipid metabolism, mitochondrial function, and inflammatory responses.

This Special Issue aims to highlight the latest research on the effects of various exercise methods on metabolic health, encompassing molecular, physiological, and clinical perspectives. We welcome submissions of original research articles, clinical trials, systematic reviews, and meta-analyses that explore the role of exercise in modulating metabolic processes. Studies focusing on exercise-induced adaptations in metabolic syndrome, insulin sensitivity, energy expenditure, adipose tissue metabolism, muscle physiology, and cardiovascular function are particularly welcome.

Potential topics include but are not limited to the following:

The impact of different exercise modalities (aerobic, resistance, HIIT, WB-EMS, etc.) on metabolic biomarkers;

  • Exercise-induced adaptations in mitochondrial function and energy metabolism;
  • The role of exercise in insulin sensitivity and glucose homeostasis;
  • The interplay between exercise, inflammation, and oxidative stress in metabolic disorders;
  • Exercise as an intervention for obesity, type 2 diabetes, and metabolic syndrome;
  • Environmental and physiological factors affecting metabolic adaptations to exercise;
  • The influence of age and sex on metabolic responses to exercise;
  • The long-term effects of structured physical activity programs on metabolic health.

This Special Issue aims to provide a comprehensive understanding of how various exercise methods contribute to metabolic regulation and disease prevention. By compiling cutting-edge research, we hope to provide insights for optimizing exercise interventions to enhance metabolic health.

We encourage researchers in exercise physiology, sports science, endocrinology, and clinical medicine to contribute their findings. Please refer to the journal’s submission guidelines for details on manuscript preparation and submission.

Dr. Hun-Young Park
Dr. Won-Sang Jung
Guest Editors

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Keywords

  • exercise physiology
  • metabolism
  • insulin sensitivity
  • energy expenditure
  • cardiovascular health
  • resistance training
  • high-intensity interval training
  • hypoxia
  • mitochondrial function
  • metabolic syndrome

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Published Papers (1 paper)

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Research

19 pages, 2384 KiB  
Article
Effects of a 6-Week Concurrent Training Program Combining Resistance and Various Modalities of Aerobic Exercise in Obese Women with Prehypertension: A Randomized Controlled Trial
by Jinhyuk Yu, Eunjoo Lee, Jae-Ho Choi, Yerin Sun, Seungyeon Woo, Sohyang Cho, Deunsol Hwang, Sung-Woo Kim, Jisu Kim, Kiwon Lim and Hun-Young Park
Metabolites 2025, 15(4), 278; https://doi.org/10.3390/metabo15040278 - 17 Apr 2025
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Abstract
Background/Objectives: Our study aimed to verify the effects of 6 weeks of concurrent training composed of resistance training (RT) and different modalities of aerobic exercise (moderate-intensity continuous training (MICT) or high-intensity interval training (HIIT)) on body composition, blood pressure, vascular function, autonomic [...] Read more.
Background/Objectives: Our study aimed to verify the effects of 6 weeks of concurrent training composed of resistance training (RT) and different modalities of aerobic exercise (moderate-intensity continuous training (MICT) or high-intensity interval training (HIIT)) on body composition, blood pressure, vascular function, autonomic nervous system (ANS) function, blood lipid levels, cardiometabolic index (CMI), and health-related fitness in obese middle-aged women with prehypertension. Methods: We selected 26 middle-aged women with obesity and prehypertension and divided them equally into the RT + MICT (n = 13) and RT + HIIT (n = 13) groups. The concurrent training program consisted of warm-up, RT, aerobic exercise (MICT or HIIT), and cool-down, and was performed for 6 weeks, three times a week, 85–100 min per session. The measured dependent parameters were analyzed before and after training. Results: Concurrent training (RT + MICT and RT + HIIT) for 6 weeks showed significant improvements in body composition, blood pressure, vascular function, ANS function, CMI, and health-related fitness. However, the RT + HIIT group showed a relatively greater improvement in blood lipid levels compared to the RT + MICT group. Conclusions: Our study confirmed that both RT + MICT and RT + HIIT yielded similar positive effects on most health-related parameters in obese middle-aged women with prehypertension. Among them, RT + HIIT appeared to be relatively more effective in improving blood lipid profiles. Full article
(This article belongs to the Special Issue Effects of Various Exercise Methods on Metabolic Health)
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