Innovative Approaches in Regulatory Toxicology-Oriented Metabolomics
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Metabolomic Profiling Technology".
Deadline for manuscript submissions: closed (15 August 2022) | Viewed by 459
Editors
2. Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland
3. Swiss Centre for Applied Human Toxicology (SCAHT), Basel, Switzerland
Interests: metabolomics; toxicology; fluorescence method development; mass spectrometry; analytical chemistry; capillary electrophoresis; liquid chromatography method validation; systems biology; sample preparation; multivariate data analysis
Special Issue Information
Dear Colleagues,
Metabolomics has become a mature and powerful discipline granting access to formerly unimaginable insights into living systems and their phenotypic transformations. Thanks to its sensitivity to detect such alterations, and to its ability to take minute samples of almost any nature, metabolomics has found countless applications in toxicology. Nevertheless, while widely adopted in academic research, metabolomic approaches still encounter some reluctance to find their way into regulatory settings, largely because of the lack of transparency and harmonization in workflows and reporting.
This Special Issue welcomes papers covering the most recent advancements facilitating the adoption of metabolomics in regulatory sciences, including applications (mechanisms of action, chemical grouping, read-across, points of departure, toxicokinetics, 3R), methodological developments (chemical coverage, analytical throughput, sensitivity, annotation) and harmonization (best practices, experimental design, sample preparation, analytical protocols, data analysis and reporting, multi-omics integration), as well as environmental and veterinary toxicometabolomics.
Dr. Víctor González-Ruiz
Dr. Eulalia Olesti
Guest Editors
Manuscript Submission Information
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