Special Issue "Scottish Metabolomics Network Annual Meeting—New Innovations in Metabolomics"

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Frontiers in Metabolomics".

Deadline for manuscript submissions: 15 December 2020.

Special Issue Editors

Prof. Dr. Phil Whitfield
Website
Guest Editor
Division of Biomedical Sciences, University of the Highlands and Islands, UK
Interests: lipidomics; lipid metabolism; metabolic diseases
Dr. David Watson
Website
Guest Editor
Strathclyde Institute of Pharmacy and Biomedical Sciences, Glasgow, United Kingdom
Interests: mass spectrometry; metabolomics; exercise; immunology; propolis
Dr. Nicholas J W Rattray
Website
Guest Editor
University of Strathclyde, Glasgow, UK
Interests: metabolomics; mass spectrometry; biogerontology; colon cancer
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Special Issue Information

Dear Colleagues,

Since its inaugural meeting in 2015, the Scottish Metabolomics Network Symposium has grown to become one of the largest metabolomics meetings in the UK, with average attendances of >100 attracting delegates from universities, research institutes, and industry.

The meeting showcases the breadth of metabolomics in Scotland. This year’s event will take place over three days, with a one-day workshop on data modelling and plenary lecture from Dr Tim Ebbels kicking the meeting off. Throughout the subsequent two days of talks, posting, and discussions, a diverse range of small molecule bioanalysis will be covered ranging from biomarker and cell-based metabolomics through to plant and nutrition, microbial, technological, and computational approaches, concluding with a plenary from Prof Roy Goodacre on aspects of large-scale phenotyping experiments.

Such experimental variety is testament to the dedication, development, progression, and adoption of metabolomics technologies in Scotland and bodes very well for the future.

This Special Issue of Metabolites will be open to selected papers from this conference , in addition to other works that fall within the scope of this issue from outside this meeting.

Dr. Phil Whitfield
Dr. David Watson
Dr. Nicholas J W Rattray
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Human health
  • Cancer metabolism
  • Biomarker research
  • Microbial metabolomics
  • Sports metabolism
  • Nutritional metabolomics
  • Lipidomics
  • Advantages in technology.

Published Papers (1 paper)

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Research

Open AccessArticle
Surviving Starvation: Proteomic and Lipidomic Profiling of Nutrient Deprivation in the Smallest Known Free-Living Eukaryote
Metabolites 2020, 10(7), 273; https://doi.org/10.3390/metabo10070273 - 03 Jul 2020
Abstract
Marine phytoplankton, comprising cyanobacteria, micro- and pico-algae are key to photosynthesis, oxygen production and carbon assimilation on Earth. The unicellular green picoalga Ostreococcus tauri holds a key position at the base of the green lineage of plants, which makes it an interesting model [...] Read more.
Marine phytoplankton, comprising cyanobacteria, micro- and pico-algae are key to photosynthesis, oxygen production and carbon assimilation on Earth. The unicellular green picoalga Ostreococcus tauri holds a key position at the base of the green lineage of plants, which makes it an interesting model organism. O. tauri has adapted to survive in low levels of nitrogen and phosphorus in the open ocean and also during rapid changes in the levels of these nutrients in coastal waters. In this study, we have employed untargeted proteomic and lipidomic strategies to investigate the molecular responses of O. tauri to low-nitrogen and low-phosphorus environments. In the absence of external nitrogen, there was an elevation in the expression of ammonia and urea transporter proteins together with an accumulation of triglycerides. In phosphate-limiting conditions, the expression levels of phosphokinases and phosphate transporters were increased, indicating an attempt to maximise scavenging opportunities as opposed to energy conservation conditions. The production of betaine lipids was also elevated, highlighting a shift away from phospholipid metabolism. This finding was supported by the putative identification of betaine synthase in O. tauri. This work offers additional perspectives on the complex strategies that underpin the adaptive processes of the smallest known free-living eukaryote to alterations in environmental conditions. Full article
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