Metabolomics Meets Neuropsychiatry

Dear Colleagues,

Neuropsychiatric disorders (NPDs) such as schizophrenia, depression, bipolar, anxiety, substance abuse, attention deficit hyperactivity disorder, etc. have complex pathophysiology limiting the understanding of pathomechanisms and the discovery of novel biomarkers and therapeutic alternatives. In recent years, metabolomics has emerged as a pivotal tool in bridging the gaps between NPDs and metabolic comorbidities. The study of metabolites-originated neurotransmitters, peptides, amino acids, lipids, and fatty acids in the targeted brain tissues, blood cells, and serum samples has significantly been employed in the clinical diagnosis of NPDs. In addition, emerging evidence suggesting the association of gut microbiota and gut-bacteria-derived metabolites with NPDs has also attracted the scientific community. The study of drug metabolites in body fluids has also been a valuable tool in assessing the ratios of therapeutic action and adverse effects.

This Special Issue, “Metabolomics Meets Neuropsychiatry,” will highlight the implications of targeted/untargeted metabolomic approaches in understanding the mechanisms behind NPDs, as well as the therapeutic and adverse effects of drugs and identifying novel biomarkers. We invite the submission of original research and review articles covering this area of research, as well as studies investigating the effects of pharmacological interventions on altering the metabolites (neurotransmitters, lipids, amino acids, etc.) in NPDs and associated metabolic disorders. Furthermore, studies investigating the desired/adverse effects of drugs and drug metabolites in treating NPDs are also encouraged for submission.

Dr. Anurag Kuhad
Dr. Raghunath Singh
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.