Preclinical and Clinical Application of Metabolomics in Medicine
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Pharmacology and Drug Metabolism".
Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 9118
Special Issue Editors
2. Biomic_AUTh, Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, 10th km Thessaloniki-Thermi Rd, 57001 Thessaloniki, Greece
Interests: systems biology; bioinformatics; biostatistics; data analysis; molecular genetics; biochemistry; metabolomics and medicine
2. Greece & Biomic_AUTh, Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, 10th km Thessaloniki-Thermi Rd., 57001 Thessaloniki, Greece
Interests: LC-MS/MS; GC-MS and NMR metabolic profiling; biochemical interpretation of metabolomics data; designing and carrying out procedures on rodents
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolomics encompasses the comprehensive analysis of small molecules, revealing a biochemical snapshot of living organisms in a wide range of fields.
In preclinical studies, in vitro, in vivo, ex vivo, and in silico models, metabolomics is used for a wide spectrum of applications such as the discovery of biomarkers of pathophysiological conditions or the evaluation of the efficacy or toxicity of a therapeutic approach.
In clinical studies, metabolomics can offer novel panels of prognostic and diagnostic disease biomarkers, as well as personalized quantitative results of treatment response to medications, which are highly sought after in medicine.
Metabolic profiling in clinical practice has proven challenging so far, and has yet to reach its foretold potential. Recent advances in the utilization of animal models and machine learning could be valuable in navigating the turbulent waters of metabolomics.
This Special Issue of Metabolites will publish reviews and original articles covering the latest developments in biomarker discovery in preclinical and clinical research, obtained via the application of state-of-the-art metabolomics-based analytical methods.
Dr. Eleftherios Panteris
Dr. Olga Deda
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- metabolomics
- metabolic profiling
- lipidomics
- biomarker discovery
- personalized medicine
- precision medicine
- animal models
- machine learning
- analytical techniques
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