Metabolomics in Respiratory, Cardiovascular and Metabolic Disorders
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: closed (1 December 2025) | Viewed by 1252
Special Issue Editor
Interests: biomarkers; COPD; asthma; lung cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Research and developments in biomarker discovery are central in modern health care for personalized and precision medicine. This is especially important in very prevalent chronic diseases that involve respiratory, cardiovascular, and endocrine–metabolic disorders. However, traditional research based on more conventional techniques and hypothesis-driven approaches has failed in this objective. Omics approaches, in contrast, are particularly relevant and useful tools to identify new molecular biomarkers to improve the screening and diagnosis, enable more precise phenotyping (i.e., heterogeneity of clinical presentations) and prognosis, and even suggest new potential therapeutic targets. In this context, genomics, transcriptomics, and proteomics have provided new insights in the last decade, contributing to advances in biomedicine. Metabolomics, in turn, represents an attractive strategy for profiling a wider panel of molecules closely related to pathophysiological conditions in patient fluid or tissue samples.
This Special Issue of Metabolites will be devoted to the development and use of metabolomics approaches at both translational and clinical levels. The specific topics will include metabolomics biomarker discovery in very prevalent disorders targeting the respiratory system (COPD, asthma, lung cancer, and interstitial fibrosis), the cardiovascular system (chronic heart failure, ischemic heart disease, cardiomyopathies), and the endocrine–metabolic framework (dyslipidemia, diabetes mellitus, hyperthyroidism, and hypothyroidism) in a personalized medicine context. Molecular understanding of metabolic pathophysiological contexts in all these disorders will undoubtedly help in their future clinical management.
Prof. Dr. Joaquim Gea
Guest Editor
Manuscript Submission Information
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Keywords
- metabolomics
- small molecules
- mass spectrometry
- NMR
- personalized medicine
- biomarkers
- car-diovascular disorders
- respiratory diseases
- endocrine metabolic abnormalities
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