Metabolic Changes in Diet-Mediated Inflammatory Diseases
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 465
Special Issue Editor
2.Center for Advanced Studies and Technology (CAST), ‘G. d’Annunzio’ University of Chieti-Pescara, 66100 Chieti, Italy
Interests: inflammation; cancer; immune system; tumoral microenvironment; metabolic reprogramming; autoimmune disease
Special Issue Information
Dear Colleagues,
The incidence of several inflammatory disorders and autoinflammatory diseases has increased dramatically in Western countries over the past few decades. The inflammatory process negatively affects all physiological functions, causing several pathological conditions such as cancer, neurodegeneration, immune disorders, and metabolic syndromes. The strong inflammatory component present in this array of degenerative conditions is affected by lifestyles and diets. The nutritional changes that occurred in Western countries determined an increase in the consumption of energy-dense, nutrient-poor, and ultra-processed foods. Epidemiological studies correlate this “Westernized diet” to characteristic metabolic changes in inflammatory tissues with nutrient depletion, increased oxygen consumption, and oxidative stress, responsible for the activation of the immune response. Interestingly, diet metabolites can reduce or delay the onset of immune-mediated diseases, making nutritional intervention a possible strategy in immunotherapy. The purpose of this Special Issue is to take stock of the complex networks between diet, metabolic reprogramming, and immune response. It will consider original research, short communications, and reviews based on, but not limited to, understanding the intricate interplay between diet-related metabolic changes and immune response activation.
Dr. Beatrice Dufrusine
Guest Editor
Manuscript Submission Information
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Keywords
- nutrition
- Westernized diet
- inflammation
- immune system
- cancer
- metabolic reprogramming
- au-toimmune disease
- obesity
- allergies
- inflammatory bowel diseases
- celiac disease
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