Bioactive Secondary Metabolites from Marine Macro- and Microorganisms
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Pharmacology and Drug Metabolism".
Deadline for manuscript submissions: 29 May 2026 | Viewed by 62
Special Issue Editors
Interests: bioactive secondary metabolites from marine microorganisms
Special Issues, Collections and Topics in MDPI journals
Interests: marine natural products
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Marine habitats, such as the deep sea, hydrothermal vents, cold springs, and polar regions, have led to marine organisms evolving unique metabolic pathways to cope with the conditions related to special, highly competitive environments. These habitats harbor a vast number of abundant species that are the source of a wide array of structurally diverse bioactive secondary metabolites. Over 43,000 marine natural products have been reported to date, and approximately 1500 new marine natural products have been isolated per year over the last five years. Notably, marine microorganisms, including bacteria, fungi, and microalgae, have been identified as prolific sources of novel bioactive secondary metabolites in recent years. The use of marine natural products represents a crucial advancement in the field of healthcare and wellness. With the advent of new analytical methods and multi-omics technologies, screening for promising natural products and their research and development in the pharmaceutical pipeline have increased. More and more enzymatic and pharmacological mechanisms of bioactive secondary metabolites from marine macro- and microorganisms are expected to be revealed in the future.
This Special Issue aims to collect papers on the most recent findings in the field of “Bioactive Secondary Metabolites from Marine Macro- and Microorganisms”, from the discovery of new bioactive natural products from marine macro-/micro-organisms to the pharmacodynamics, pharmacokinetics, metabolisms, and mechanisms of marine-derived lead compounds, and their structure–activity relationships. We hope that this Special Issue inspires the discovery of new marine-derived novel bioactive compounds, as well as shedding light on the further research and development of marine candidate drugs. Comprehensive review papers of the latest bioactive marine natural products are also welcome.
Prof. Dr. Xiaowei Luo
Prof. Dr. Yonghong Liu
Guest Editors
Manuscript Submission Information
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Keywords
- secondary metabolites
- bioactivity
- marine natural products
- marine microorganisms
- marine organisms
- drug discovery
- lead compounds
- pharmacological mechanism
- marine drugs
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