Trauma, Critical Care, and Acute Care Surgery

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Surgery".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 604

Special Issue Editors


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Guest Editor
Emergency Medicine, University of Medicine and Pharmacy, Craiova, Romania
Interests: emergency management; mechanical ventilation; critical care medicine; cardiopulmonary resuscitation; emergency treatment; resuscitation; CPR; airway management; sepsis; helicopter emergency medical system

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Guest Editor Assistant
Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie din Craiova, Craiova, Romania
Interests: colorectal surgery; surgical oncology; laparoscopic surgery; general surgery; abdominal surgery; gastrointestinal surgery; cancer surgery; minimally invasive surgery; diagnosis; treatment

Special Issue Information

Dear Colleagues,

Major trauma has been, and remains until now, one of the primary reasons for the development of the emergency medicine specialty and for progress in anesthesiology and intensive care.

The concepts of "the golden hour" and "the platinum minutes", the evolution from the "scoop and run" model to the current "run and play" strategy, the "damage control" philosophy, and the bringing of ECMO into advanced field medicine are all part of the fundamental standard of increasing the chance of survival and rehabilitation of a patient with polytrauma.

More than in any other segment of intensive care medicine, the keystone of success is represented by the multidirectional integration in the multi-agency climate: operational; tactical—conceptual; educational; and, last but not least, by the strategies for implementing the results of scientific research in current practice from the scene of the accident.

I invite you to bring together the results of your prestigious medical, scientific, and academic research career in the spirit of the interdisciplinarity that polytrauma requires in order to outline advanced concepts and practices, lay new foundations for cutting-edge research, personalize and customize solutions, and strengthen education and comradery.

Prof. Dr. Luciana Teodora Rotaru
Guest Editor

Prof. Dr. Stelian Mogoanta
Guest Editor Assistant

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Keywords

  • golden hour
  • air medical evacuation
  • damage control
  • trauma centers
  • coagulopathy
  • pain management
  • dispatch centers
  • triage
  • incident command system
  • telemedicine

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Published Papers (1 paper)

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Research

13 pages, 296 KiB  
Article
Analysis of Massive Transfusion Protocol Utilization in Trauma Across Sociodemographic Groups
by Monique Arnold, Bharti Sharma, Matthew Conn, Kate Twelker, Navin D. Bhatia, George Agriantonis, Jasmine Dave, Juan Mestre, Zahra Shafaee and Jennifer Whittington
Medicina 2025, 61(7), 1133; https://doi.org/10.3390/medicina61071133 - 24 Jun 2025
Viewed by 328
Abstract
Background and Objectives: Blood shortages are a national crisis, creating dangerous scenarios for patients requiring the use of a massive transfusion protocol (MTP). A judicious use of blood products is critical to rescue salvageable patients while refraining from unnecessary MTP to save [...] Read more.
Background and Objectives: Blood shortages are a national crisis, creating dangerous scenarios for patients requiring the use of a massive transfusion protocol (MTP). A judicious use of blood products is critical to rescue salvageable patients while refraining from unnecessary MTP to save precious resources. This study examines effect of trauma characteristics, socioeconomic variables and markers of futility on the likelihood of activating and receiving MTP in the trauma setting. Materials and Methods: In this retrospective study, emergency department (ED) trauma activations from a database of an urban Level I trauma center were analyzed from 1 January 2017 to 30 June 2022, inclusive. In-ED mortality, RBC transfusion volumes during initial resuscitation, patient sociodemographic data, and trauma event factors were analyzed. The primary outcomes were the dichotomous outcomes of MTP activation and MTP transfusion. Univariable analyses and logistic regressions were conducted, with class balancing sensitivities applied to the multivariable regressions to adjust for imbalance in the data. p < 0.05 was considered statistically significant. Results: Among the 8670 trauma activations, there was a 0.3% in-ED mortality rate. MTP activation and MTP transfusion were associated with higher in-ED mortality rates (3.8% and 15.4%, respectively, compared to 0.2% without MTP). Younger patients, male patients, and Medicaid recipients were more likely to undergo MTP activation; Medicare patients were less likely. Penetrating trauma substantially increased the likelihood of both MTP activation (odds ratio (OR) 5.81) and transfusion (OR 3.63). The logistic regression models identified the presence of penetrating trauma, lower probability of survival, and age as the most important covariates. Models demonstrated high discriminatory value (area under the curve (AUC) of the receiver operating characteristic curve (ROC) of 0.876 for MTP activation, 0.935 for MTP transfusion) and precision (0.974 for activation, 0.994 for transfusion), with class balancing further improving model performance and precision scores. Conclusions: These results are significant as assessing the futility of MTP should be equitable, and future transfusion guidelines should consider salvageability in cases with a low probability of survival despite age and mechanism. Full article
(This article belongs to the Special Issue Trauma, Critical Care, and Acute Care Surgery)
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