The Therapeutic Landscapes and Patient Management in Psychiatry and Mental Health

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Psychiatry".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 2599

Special Issue Editors


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Guest Editor
Department of Psychiatry and Psychology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Interests: affective disorders; psychotic disorders; anxiety; public health management; cognitive disorders; implications of neurodevelopmental disorders; comorbidities in psychiatry

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Guest Editor
Faculty of Medicine, Clinical Hospital of Psychiatry and Neurology Brașov, Transilvania University of Brașov, Brașov, Romania
Interests: schizophrenia; affective disorders; dementia; psychopharmacology

Special Issue Information

Dear Colleagues,

We believe that the introduction of a new Special Issue that focuses on mental health is crucial given the difficulties that the healthcare system is facing due to the rising prevalence of mental health disorders in patients with both acute and chronic illnesses.

A mental illness not only causes disruptions in the family but also society. Since psychiatry has developed alongside technological advancement, chronic disorders can now be treated with monotherapy.

Revolutionary chemicals reported to have fewer negative effects are helpful in this regard. Affective disorders and psychotic illnesses need prompt, specialized attention, just like any other chronic pathology, in order to help the patient.

Despite its decreasing relevance, the inherent stigma around psychiatry remains a social concern.

This Special Issue’s goal is to showcase current developments, cutting-edge theories of diagnosis, creative treatment strategies and innovative expectations related to affective, cognitive and psychotic disorders, chronic afflictions and comorbidities in psychiatry.

Dr. Mihnea Costin Manea
Prof. Dr. Petru Ifteni
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • affective disorders
  • psychotic illnesses
  • stigma
  • treatment strategies
  • cognitive disorders
  • comorbidities in psychiatry

Published Papers (3 papers)

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Research

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13 pages, 682 KiB  
Article
Inside the Hospitalization Voyage of Schizophrenia Care: A Single-Center Journey
by Răzvan Pop, Cătălina Angela Crișan, Ioana Valentina Micluția, Emilia Pop, Mihaela Iancu and Sorana D. Bolboacă
Medicina 2024, 60(8), 1214; https://doi.org/10.3390/medicina60081214 - 26 Jul 2024
Abstract
Schizophrenia poses significant challenges for individuals and caregivers, often leading to recurrent hospitalizations. Limited information on patients with schizophrenia and multiple hospitalizations in Romania is available in the scientific literature. Our study aimed to evaluate the characteristics of patients with schizophrenia with multiple [...] Read more.
Schizophrenia poses significant challenges for individuals and caregivers, often leading to recurrent hospitalizations. Limited information on patients with schizophrenia and multiple hospitalizations in Romania is available in the scientific literature. Our study aimed to evaluate the characteristics of patients with schizophrenia with multiple hospitalizations in a single center in Cluj-Napoca, analyzing if specific patterns exist between patients with two or more hospitalizations or between men and women. We conducted a retrospective study on patients diagnosed with schizophrenia according to the 10th revision of the International Classification of Diseases (ICD 10), hospitalized at the County Emergency Hospital of Cluj-Napoca, Romania, between 2018 and 2022. Data on demographics, somatic comorbidities, symptom severity using the positive and negative syndrome scale (PANSS) or the brief psychiatric rating scale (BPRS), antipsychotic medication, and adverse effects were collected. We evaluated 62 patients, aged from 23 to 57 years, with 157 hospitalizations (ranging from two to seven per patient). No familial history of schizophrenia (56.5%) or bipolar disorder (71%) was reported by most patients. Forty-eight patients were male, and 45 had two hospitalizations. Age, sex, living place and conditions, season of birth, and marital status were similar in patients with two or more than two hospitalizations (p-values > 0.10). Significant differences were observed between patients with two or more than two hospitalizations regarding smoking (63.3% vs. 79.1%, p-value = 0.0029) and symptoms of fear at admission (40.0% vs. 65.7%, p-value = 0.0015). We observed lower scores in the overall PANSS and BPRS scores at discharge compared to admission (p-values < 0.001), regardless of the group (two or more than two hospitalizations, men vs. women). Men and women showed differences in hospitalization stays (median 17.25 vs. 15 days, p-value < 0.001) and BPRS scores at admission (p-value = 0.012) and discharge (p-value = 0.016). Fewer First-Generation Antipsychotics were prescribed for those with two admissions, and nearly half reported adverse effects, notably tachycardia (29%), with similar occurrence within groups. Our results showed that the candidate for multiple hospitalizations is a male, with a mean age of 37 years, unmarried, and living with someone in urban settings, more likely a smoker who exhibits fear symptoms. Full article
12 pages, 1199 KiB  
Article
Effectiveness of Electroencephalography Neurofeedback for Improving Working Memory and Episodic Memory in the Elderly: A Meta-Analysis
by Yu-Ru Lin, Tien-Wei Hsu, Che-Wei Hsu, Peng-Yu Chen, Ping-Tao Tseng and Chih-Sung Liang
Medicina 2024, 60(3), 369; https://doi.org/10.3390/medicina60030369 - 22 Feb 2024
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Abstract
Background and Objective: Existing evidence indicates the potential benefits of electroencephalography neurofeedback (NFB) training for cognitive function. This study aims to comprehensively review all available evidence investigating the effectiveness of NFB on working memory (WM) and episodic memory (EM) in the elderly [...] Read more.
Background and Objective: Existing evidence indicates the potential benefits of electroencephalography neurofeedback (NFB) training for cognitive function. This study aims to comprehensively review all available evidence investigating the effectiveness of NFB on working memory (WM) and episodic memory (EM) in the elderly population. Material and Methods: A systematic search was conducted across five databases to identify clinical trials examining the impact of NFB on memory function in healthy elderly individuals or those with mild cognitive impairment (MCI). The co-primary outcomes focused on changes in WM and EM. Data synthesis was performed using a random-effects meta-analysis. Results: Fourteen clinical trials (n = 284) were included in the analysis. The findings revealed that NFB was associated with improved WM (k = 11, reported as Hedges’ g = 0.665, 95% confidence [CI] = 0.473 to 0.858, p < 0.001) and EM (k = 12, 0.595, 0.333 to 0.856, p < 0.001) in the elderly, with moderate effect sizes. Subgroup analyses demonstrated that NFB had a positive impact on both WM and EM, not only in the healthy population (WM: k = 7, 0.495, 0.213 to 0.778, p = 0.001; EM: k = 6, 0.729, 0.483 to 0.976, p < 0.001) but also in those with MCI (WM: k = 6, 0.812, 0.549 to 1.074, p < 0.001; EM: k = 6, 0.503, 0.088 to 0.919, p = 0.018). Additionally, sufficient training time (totaling more than 300 min) was associated with a significant improvement in WM (k = 6, 0.743, 0.510 to 0.976, p < 0.001) and EM (k = 7, 0.516, 0.156 to 0.876, p = 0.005); however, such benefits were not observed in groups with inadequate training time. Conclusions: The results suggest that NFB is associated with enhancement of both WM and EM in both healthy and MCI elderly individuals, particularly when adequate training time (exceeding 300 min) is provided. These findings underscore the potential of NFB in dementia prevention or rehabilitation. Full article
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Review

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12 pages, 1036 KiB  
Review
Exploring the Feasibility of Estrogen Replacement Therapy as a Treatment for Perimenopausal Depression: A Comprehensive Literature Review
by Xiuting Xiang, Praneetha Palasuberniam and Rahmawati Pare
Medicina 2024, 60(7), 1076; https://doi.org/10.3390/medicina60071076 - 30 Jun 2024
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Abstract
Perimenopausal depression (PMD) is a psychological disorder that occurs in women during perimenopause. In addition to the common clinical symptoms of depression, it often manifests as a perimenopausal complication, and its notable cause is the decline in estrogen levels. Despite numerous studies and [...] Read more.
Perimenopausal depression (PMD) is a psychological disorder that occurs in women during perimenopause. In addition to the common clinical symptoms of depression, it often manifests as a perimenopausal complication, and its notable cause is the decline in estrogen levels. Despite numerous studies and trials confirming the benefits of estrogen replacement therapy (ERT) for PMD, ERT remains unapproved for treating PMD. Therefore, we conducted a literature search using selected keywords in PubMed and Google Scholar to write a review discussing the feasibility of using ERT for PMD. This review examines the potential of ERT for PMD in terms of its underlying mechanisms, efficacy, safety, and time window. These four aspects suggest that ERT is a viable option for PMD treatment. However, the risk of thrombosis and stroke with ERT is a matter of contention among medical experts, with a paucity of clinical data. Consequently, further clinical trial data are required to ascertain the safety of ERT. Full article
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